Digestive Diseases and Sciences

, Volume 47, Issue 1, pp 20–26

Quality of Life in Functional Dyspepsia


  • Joan Monés
    • Department of Gastroenterology, Hospital de la Santa Creu i Sant PauUniversidad Autónoma de Barcelona, Sant Antoni Ma Claret 167
  • Ana Adan
    • Department of Psychiatry and Clinical PsychobiologyUniversidad Autónoma de Barcelona
  • José L. Segú
    • Division of Pharma Consult ServicesPharma Research
  • Juan S. López
    • Division of Pharma Consult ServicesPharma Research
  • Maite Artés
    • Division of Pharma Consult ServicesPharma Research
  • Tina Guerrero
    • Division of Pharma Consult ServicesPharma Research

DOI: 10.1023/A:1013294815971

Cite this article as:
Monés, J., Adan, A., Segú, J.L. et al. Dig Dis Sci (2002) 47: 20. doi:10.1023/A:1013294815971


Our purpose was to assess the quality of life of functional dyspepsia patients using the SF-36 generic scale and the Gastrointestinal Symptoms Rating Scale (GSRS). In all, 328 dyspeptic patients were included in a multicenter, prospective, observational study. Both scales were filled out at baseline and one and three months after a prokinetic agent was given as a single-drug therapy. A total of 250 patients completed the study. An improvement in all SF-36 dimensions was observed, although the final scores were lower than the population reference values. Physical role (27% change), emotional role (20%), and physical pain (16%) dimensions showed the greater change. The GSRS total and domain scores also showed significant decreases. The best predictors of quality of life improvement were certain basal symptoms, drug compliance, and the absence of idiopathic dyspepsia. In conclusion, both the generic and the specific scales provide useful and sensitive measures of quality of life in functional dyspepsia patients on single-drug treatment.

functional dyspepsiagastrointestinal symptomsprokinetic agentsquality of life

Copyright information

© Plenum Publishing Corporation 2002