Pharmacy World and Science

, Volume 23, Issue 3, pp 122–122

Pre‐emptive metoclopramide and ondansetron for nausea and vomiting associated with iloprost infusions

  • Chris Roome
  • John Thompson

DOI: 10.1023/A:1011231507085

Cite this article as:
Roome, C. & Thompson, J. Pharm World Sci (2001) 23: 122. doi:10.1023/A:1011231507085


Objective: To assess the effectiveness of ondansetron in relieving symptoms of nausea and vomiting which were refractory to metoclopramide and cyclizine, in a patient receiving iloprost infusions.Method: Case observation in a series of 7 infusions.Results: Ondansetron reduced WHO symptom scores of vomiting from Grade 2 to Grade 0. Symptoms of nausea were abolished on some occasions.Conclusion: Ondansetron was found to be effective at abolishing symptoms of vomiting and partially effective against symptoms of nausea. It may prove to be a useful treatment modality to allow the patient to tolerate further infusions of iloprost where nausea and vomiting has failed to respond to other agents.


Copyright information

© Kluwer Academic Publishers 2001

Authors and Affiliations

  • Chris Roome
    • 1
  • John Thompson
    • 1
  1. 1.Royal Devon & Exeter Hospital (Wonford)Exeter, EnglandUK