Digestive Diseases and Sciences

, Volume 46, Issue 7, pp 1458–1465

Electrogastrographic Characteristics in Patients of Stomach Cancer

Authors

  • Full-Young Chang
    • Division of GastroenterologyTaipei Veterans General Hospital and School of Medicine National Yang Ming University
  • Ching-Liang Lu
    • Division of GastroenterologyTaipei Veterans General Hospital and School of Medicine National Yang Ming University
  • Chih-Yen Chen
    • Division of GastroenterologyTaipei Veterans General Hospital and School of Medicine National Yang Ming University
  • Shou-Dong Lee
    • Division of GastroenterologyTaipei Veterans General Hospital and School of Medicine National Yang Ming University
  • Chew-Wun Wu
    • Division of General SurgeryTaipei Veterans General Hospital and School of Medicine National Yang Ming University
  • Shuenn-Tsong Young
    • Institute of Biomedical EngineeringNational Yang Ming University
  • Han Chang Wu
    • Department of Electrical EngineeringNational Taiwan University
  • Te-Son Kuo
    • Department of Electrical EngineeringNational Taiwan University
Article

DOI: 10.1023/A:1010687804141

Cite this article as:
Chang, F., Lu, C., Chen, C. et al. Dig Dis Sci (2001) 46: 1458. doi:10.1023/A:1010687804141
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Abstract

Using a homemade electrogastrography (EGG) system, we studied the characteristics of myoelectrical rhythm in gastric cancer (GC) patients. Based on a short-term Fourier transform, recorded slow waves could be automatically analyzed to obtain the following parameters: dominant frequency/power, percent of normal rhythm (2.4–3.7 cpm), power ratio, etc. Fifty histologically confirmed GC patients (34 men, 16 women) were enrolled before surgical intervention to measure their fasting and postprandial EGG parameters for 30 min. The cancerous parameters of GC patients were then obtained postoperatively. In addition, 46 healthy subjects were enrolled for comparison. When compared to controls, GC patients had the following characteristics: absence of postprandial increase in dominant frequency (GC: 3.04 ± 0.47 vs 3.07 ± 0.44 cpm, NS; controls: 3.02 ± 0.31 vs 3.21 ± 0.25 cpm, P < 0.001), marked power response after meal (P < 0.05), and obvious power ratio (4.58 ± 7.38 vs 2.27 ± 2.05, P < 0.05). Multivariate analysis indicated that advanced GC was the factor responsible for the obvious dominant power enhancement after meal (P < 0.05). Other demographic, clinical, and cancerous factors did not influence EGG parameters. We conclude that apparent arrhythmia is not encountered in GC patients, although they mainly exhibit obvious postprandial power response. Advanced GC is likely responsible for this power enhancement on EGG recording.

electrogastrographygastric cancergastrointestinal motilityHelicobacter pylorislow wave
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© Plenum Publishing Corporation 2001