Computing the Cox Model for Case Cohort Designs
- Cite this article as:
- Therneau, T.M. & Li, H. Lifetime Data Anal (1999) 5: 99. doi:10.1023/A:1009691327335
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Prentice (1986) proposed a case-cohort design as an efficient subsampling mechanism for survival studies. Several other authors have expanded on these ideas to create a family of related sampling plans, along with estimators for the covariate effects. We describe how to obtain the proposed parameter estimates and their variance estimates using standard software packages, with SAS and SPLUS as particular examples.