Biotechnology Techniques

, Volume 13, Issue 4, pp 235–238

Use of alkaline proteases for ultrafiltration membrane cleaning

  • C. Ganesh Kumar
  • M.P. Tiwari

DOI: 10.1023/A:1008990327859

Cite this article as:
Kumar, C.G. & Tiwari, M. Biotechnology Techniques (1999) 13: 235. doi:10.1023/A:1008990327859


Ability of alkaline proteases to clean ultrafiltration membranes fouled during milk processing was determined in two alkaline UF membrane cleaner, Alconox and Ultrasil. Optimum hydrolysis of milk proteins was observed with 5 g enzyme/l and showed a linear increase in water flux from 37.6 l m−2 h to 212.4 l m−2 h after 0.67 h. Enzyme performance was synergistically enhanced in combination with Alconox cleaner and exhibited 100% flux restoration.

alkaline proteasesBacillusfoulingmembrane cleaningultrafiltration

Copyright information

© Kluwer Academic Publishers 1999

Authors and Affiliations

  • C. Ganesh Kumar
    • 1
  • M.P. Tiwari
    • 1
  1. 1.Dairy Microbiology DivisionNational Dairy Research Institute, KarnalHaryana)India