Quality of Life Research

, Volume 9, Issue 5, pp 579–586

Health values of patients with bipolar disorder

  • Joel Tsevat
  • Paul E. Keck
  • Richard W. Hornung
  • Susan L. McElroy
Article

DOI: 10.1023/A:1008979825704

Cite this article as:
Tsevat, J., Keck, P.E., Hornung, R.W. et al. Qual Life Res (2000) 9: 579. doi:10.1023/A:1008979825704

Abstract

Background: Despite a growing number of studies of patients' health values (utilities), little is known about health values of patients with mental illness, particularly bipolar (manic-depressive) disorder. Methods: We administered a computerized rating scale, time tradeoff, and standard gamble to 53 patients. Patients were asked to rate or value their current state of health overall and then their current mental health. In addition, we administered the SF-36; Inventory of Depressive Symptoms (IDS-C); Positive and Negative Syndrome Scale (PANSS); Young Mania Rating Scale (YMRS); and Global Assessment of Functioning Scale. Results: The patients' median (25th, 75th percentile) age was 43 (37, 50); 62% were female. Mean (±SD) health ratings for current overall health were 68.0 (±20.3) vs. 61.0 (±25.7) for current mental health (p-value for difference = 0.02). On the time tradeoff, scores for current overall health averaged 0.71 (±0.37) vs. 0.61 (±0.39) for current mental health (p = 0.02); on the standard gamble, mean scores were 0.77 (±0.32) for current overall health vs. 0.70 (±0.35) for current mental health (p = 0.11). In univariate analyses, rating scale, time-tradeoff, and standard gamble scores for both current overall health and for current mental health were correlated with the SF-36 and all psychiatric scales (|r| = 0.22–0.76) except the YMRS (|r| ≤ 0.13). In multivariable analyses, health values for current overall health were related to factors different from those that were related to health values for current mental health (R2 = 0.38–0.65), and none of the health value measures was related to the YMRS. Conclusion: Health values of patients with bipolar disorder are higher for their current health overall than for their current state of mental health. Health values are related to certain health status attributes and to level of depression but perhaps not to level of mania.

Bipolar disorder Health status Mental health Outcome assessment (health care) Quality of life 

Copyright information

© Kluwer Academic Publishers 2000

Authors and Affiliations

  • Joel Tsevat
    • 1
    • 2
  • Paul E. Keck
    • 3
  • Richard W. Hornung
    • 2
  • Susan L. McElroy
    • 3
  1. 1.Section of Outcomes Research, Division of General Internal Medicine, Department of Internal MedicineUniversity of Cincinnati Medical CenterCincinnatiUSA
  2. 2.Institute for Health Policy and Health Services ResearchUniversity of Cincinnati Medical CenterCincinnatiUSA
  3. 3.Biological Psychiatry Program, Department of PsychiatryUniversity of Cincinnati Medical CenterCincinnatiUSA