Cancer Causes & Control

, Volume 9, Issue 1, pp 49–56

Smoking and the risk of leukemia, lymphoma, and multiple myeloma (Sweden)

  • Johanna Adami
  • Olof Nyrén
  • Reinhold Bergström
  • Anders Ekbom
  • Göran Engholm
  • Anders Englund
  • Bengt Glimelius
Article

DOI: 10.1023/A:1008897203337

Cite this article as:
Adami, J., Nyrén, O., Bergström, R. et al. Cancer Causes Control (1998) 9: 49. doi:10.1023/A:1008897203337

Abstract

While several epidemiologic studies have indicated a link between smoking and the risk of developing hema-tolymphoproliferative cancers (chiefly leukemias, lymphomas, and multiple myelomas), in particular myeloid leukemia, the role of tobacco in the etiology of these neoplasms remains unclear. To evaluate the potential impact of tobacco use on development of leukemia, lymphoma, and multiple myeloma, we conducted a cohort study of 334,957 Swedish construction workers using prospectively collected exposure-information with complete long-term follow-up. A total of 1,322 incident neoplasms occurred during the study period, 1971-91. We found no significant association between smoking status, number of cigarettes smoked, or duration of smoking and the risk of developing leukemias, lymphomas, or multiple myeloma. There was a suggestion of a positive association between smoking and the risk of developing Hodgkin's disease, although the rate ratios were not significantly elevated, except for young current smokers. No positive dose-risk trends emerged. Our study provides no evidence that smoking bears any major relationship to the occurrence of leukemias, non-Hodgkin's lymphomas, or multiple myeloma.

Leukemia lymphoma men multiple myeloma smoking Sweden 

Copyright information

© Chapman and Hall 1998

Authors and Affiliations

  • Johanna Adami
    • 1
  • Olof Nyrén
    • 1
  • Reinhold Bergström
    • 2
  • Anders Ekbom
    • 3
  • Göran Engholm
    • 4
  • Anders Englund
    • 4
  • Bengt Glimelius
    • 5
  1. 1.Department of Medical EpidemiologyKarolinska InstitutetStockholmSweden
  2. 2.Department of StatisticsUppsala University UppsalaSweden
  3. 3.Harvard School of Public HealthBostonUSA
  4. 4.National Board of Health and Welfare StockholmSweden
  5. 5.Department of OncologyUniversity Hospital UppsalaSweden

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