Cancer Causes & Control

, Volume 9, Issue 1, pp 11–18

Physical activity and prostate cancer in the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study (Finland)

Authors

  • Terryl J. Hartman
    • Division of Clinical SciencesNational Cancer Institute Bethesda
  • Demetrius Albanes
    • Division of Clinical SciencesNational Cancer Institute Bethesda
  • Matti Rautalahti
    • National Public Health Institute Helsinki
  • Joseph A. Tangrea
    • Division of Clinical SciencesNational Cancer Institute Bethesda
  • Jarmo Virtamo
    • National Public Health Institute Helsinki
  • Rachael Stolzenberg
    • Division of Clinical SciencesNational Cancer Institute Bethesda
  • Philip R. Taylor
    • Division of Clinical SciencesNational Cancer Institute Bethesda
Article

DOI: 10.1023/A:1008889001519

Cite this article as:
Hartman, T.J., Albanes, D., Rautalahti, M. et al. Cancer Causes Control (1998) 9: 11. doi:10.1023/A:1008889001519

Abstract

The association between physical activity and prostate cancer was evaluated in the trial-based cohort of the Alpha-Tocopherol, Beta-Carotene (ATBC) Cancer Prevention Study (n = 29,133). During up to nine years of follow-up, 317 men developed incident prostate cancer. The relationship between occupational, leisure, and combined activity and prostate cancer was assessed in multivariate Cox regression models that adjusted for intervention group, benign prostatic hyperplasia, age, smoking, and urban residence. Compared with sedentary workers, relative risks (RR) and 95 percent confidence intervals (CI) for occupational walkers, walker/lifters, and heavy laborers were 0.6 (CI = 0.4-1.0), 0.8 (CI = 0.5-1.3), and 1.2 (CI = 0.7-2.0), respectively. Among working men, leisure activity (active cf sedentary) was associated inversely with risk (RR = 0.7, CI = 0.5-0.9). This inverse association for leisure activity was observed, with the exception of heavy laborers, for all occupational acti vity levels, and was strongest among walkers compared with men sedentary at work and leisure, and to a lesser degree among walker/lifters. These results are consistent with a protective effect of physical activity on prostate cancer.

ExerciseFinlandmenphysical activityprostate cancer

Copyright information

© Chapman and Hall 1998