Biodegradation

, Volume 9, Issue 6, pp 513–525

On the detection of environmental effects on complex matrices combining off-line liquid chromatography and 1H-NMR

  • Arjen Lommen
  • Joop M. Weseman
  • Geo O. Smith
  • Hub P.J.M. Noteborn
Article

DOI: 10.1023/A:1008398321079

Cite this article as:
Lommen, A., Weseman, J.M., Smith, G.O. et al. Biodegradation (1998) 9: 513. doi:10.1023/A:1008398321079

Abstract

An off-line combination of 400 MHz proton (1H)-NMR spectroscopy and liquid chromatography (LC) has been used for the multi-component comparison of low-molecular weight compounds (i.e., chemical fingerprinting) in model fluid broths and (processed) tomato. The focus of the research described is on (i) devising GLP-like methods for sample handling and NMR measurements that will ensure reproducibility, (ii) an automated handling of data, (iii) validity of the designed methodology and (iv) the interpretation of large amounts of data.

automationenvironmentfingerprintingGLPLCNMRstatistics

Copyright information

© Kluwer Academic Publishers 1998

Authors and Affiliations

  • Arjen Lommen
    • 1
  • Joop M. Weseman
    • 1
  • Geo O. Smith
    • 1
  • Hub P.J.M. Noteborn
    • 1
  1. 1.State Institute for Quality Control of Agricultural Products (RIKILT-DLO)AE WageningenThe Netherlands