Tanskanen, A., Tuomilehto, J., Viinamäki, H. et al. Eur J Epidemiol (2000) 16: 789. doi:10.1023/A:1007614714579
Earlier research has implicated coffee drinking as a possible protective factor for suicide. We followed-up 43,166 subjects for the mean 14.6 years, and 213 suicides were committed. Daily coffee drinking had a J-shaped association with the risk of suicide. Using the Cox model we controlled for potential covariates, and found that among heavy coffee drinkers (≥ 8 cups/day) the risk of suicide was 58% higher compared with more moderate drinkers.