Hepatitis A infection: A seroepidemiological study in young adults in North-East Italy
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During the period from January to May 1994, the prevalence of antibodies to hepatitis A virus infection (anti-HAV) was tested by immunoenzyme assay in the serum samples of 620 apparently healthy subjects (81% males, 19% females), from 10 to 29 years old, resident in North-East Italy (Pordenone and surrounding district). The overall prevalence of anti-HAV was 3.7%. There was a significant lower prevalence in the group aged 10-19 than in the one aged 20–29 years (0.7% vs 6%; p < 0.001). Moreover, a significant sex difference was observed for the 20–29 year age group (p < 0.001). Among the various risk factors considered, family size and travelling abroad to endemic areas were significantly associated with HAV infection. Since a valid and effective vaccine against HAV infection has recently become available, anti-HAV vaccination campaigns can feasibly be programmed. However, different geographical regions present different epidemiological situations, so its use should be adapted to each region, with special attention to the cost-effectiveness of the immunisation programme. Our data suggest that in our region such vaccination could initially be proposed to high-risk subjects such as those travelling to endemic areas.
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- Hepatitis A infection: A seroepidemiological study in young adults in North-East Italy
European Journal of Epidemiology
Volume 13, Issue 8 , pp 875-879
- Cover Date
- Print ISSN
- Online ISSN
- Kluwer Academic Publishers
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- Hepatitis A
- North-East Italy
- Industry Sectors
- Author Affiliations
- 1. Institute of Hygiene, University of Padua, Italy
- 2. Department of Gastroenterology, Institute of Internal Medicine, University of Padua, Italy
- 3. Local Health Unit, Public Health Service, N. 6 West Friuli, Italy
- 4. Institute of Hygiene, University of Verona, Italy
- 5. Hygiene, University of Udine, Italy