European Journal of Epidemiology

, Volume 13, Issue 8, pp 875–879

Hepatitis A infection: A seroepidemiological study in young adults in North-East Italy


  • M.E. Moschen
    • Institute of HygieneUniversity of Padua
  • A. Floreani
    • Department of Gastroenterology, Institute of Internal MedicineUniversity of Padua
  • E. Zamparo
    • Local Health UnitPublic Health Service
  • V. Baldo
    • Institute of HygieneUniversity of Padua
  • S. Majori
    • Institute of HygieneUniversity of Verona
  • V. Gasparini
    • HygieneUniversity of Udine
  • R. Trivello
    • Institute of HygieneUniversity of Padua

DOI: 10.1023/A:1007450416869

Cite this article as:
Moschen, M., Floreani, A., Zamparo, E. et al. Eur J Epidemiol (1997) 13: 875. doi:10.1023/A:1007450416869


During the period from January to May 1994, the prevalence of antibodies to hepatitis A virus infection (anti-HAV) was tested by immunoenzyme assay in the serum samples of 620 apparently healthy subjects (81% males, 19% females), from 10 to 29 years old, resident in North-East Italy (Pordenone and surrounding district). The overall prevalence of anti-HAV was 3.7%. There was a significant lower prevalence in the group aged 10-19 than in the one aged 20–29 years (0.7% vs 6%; p < 0.001). Moreover, a significant sex difference was observed for the 20–29 year age group (p < 0.001). Among the various risk factors considered, family size and travelling abroad to endemic areas were significantly associated with HAV infection. Since a valid and effective vaccine against HAV infection has recently become available, anti-HAV vaccination campaigns can feasibly be programmed. However, different geographical regions present different epidemiological situations, so its use should be adapted to each region, with special attention to the cost-effectiveness of the immunisation programme. Our data suggest that in our region such vaccination could initially be proposed to high-risk subjects such as those travelling to endemic areas.

EpidemiologyHepatitis ANorth-East ItalySeroprevalence
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© Kluwer Academic Publishers 1997