Molecular and Cellular Biochemistry

, Volume 172, Issue 1, pp 23–35

Retroviral techniques for studying organogenesis with a focus on heart development

  • Jeanette Hyer
  • Takashi Mikawa

DOI: 10.1023/A:1006805918109

Cite this article as:
Hyer, J. & Mikawa, T. Mol Cell Biochem (1997) 172: 23. doi:10.1023/A:1006805918109


The study of development has been revolutionized by the application of molecular techniques, which make it possible to identify factors involved in the developmental process. However, in order to correctly assess the contribution of these growth factors, transcription factors, receptors or signaling molecules, it is necessary to study them in the animal as a whole; it is not enough to conclude that they must be important based on their expression patterns.

heart developmentretroviral taggingsomatic transgenicfibroblast growth factor

Copyright information

© Kluwer Academic Publishers 1997

Authors and Affiliations

  • Jeanette Hyer
    • 1
  • Takashi Mikawa
    • 1
  1. 1.Department of Cell Biology and AnatomyCornell University Medical CollegeNew YorkUSA