Article

Biotechnology Letters

, Volume 22, Issue 11, pp 931-936

First online:

Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides

  • E. AsilonuAffiliated withFungal Biotechnology Group, Biotechnology Department, University of Westminster
  • , C. BuckeAffiliated withFungal Biotechnology Group, Biotechnology Department, University of Westminster
  • , T. KeshavarzAffiliated withFungal Biotechnology Group, Biotechnology Department, University of Westminster

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Abstract

Additions of 50 to 100 μg of acid-hydrolysed alginate oligosaccharides ml−1 and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oligosaccharides also promoted biomass formation but were not used as a carbon source.

chrysogenin elicitors enhancement oligosaccharides Penicillium chrysogenum