NM23/Nucleoside Diphosphate Kinase and Signal Transduction
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- Otero, A.d.S. J Bioenerg Biomembr (2000) 32: 269. doi:10.1023/A:1005589029959
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NM23s (or NDP kinases) regulate a fascinating variety of cellular activities, includingproliferation, development, and differentiation. All these processes are modulated by external stimuli,leading to the idea that this family of proteins modulates transmembrane signaling pathways.This review summarizes the evidence indicating that NM23/NDP kinases participate intransmembrane signaling in eukaryotic cells and discusses the molecular mechanisms proposed toaccount for these actions.