Digestive Diseases and Sciences

, Volume 45, Issue 4, pp 809–818

Upper Gastrointestinal Symptoms in North America

Authors

  • Lori Frank
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Leah Kleinman
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Dara Ganoczy
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Kenneth Mcquaid
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Sheldon Sloan
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Andrew Eggleston
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Gervais Tougas
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
  • Christina Farup
    • Center for Health Outcomes ResearchMEDTAP International, Inc.
    • Gastroenterology SectionVeteran's Administration Medical Center
    • Janssen Research Foundation
    • Janssen Ortho Inc.
    • Intestinal Disease Research Programme, Division of GastroenterologyMcMaster University
Article

DOI: 10.1023/A:1005468332122

Cite this article as:
Frank, L., Kleinman, L., Ganoczy, D. et al. Dig Dis Sci (2000) 45: 809. doi:10.1023/A:1005468332122

Abstract

The aim of this study was to determine the prevalence of upper gastrointestinal symptoms (UGIS) in a general population and quantify the relationship of those symptoms to health-care utilization and quality of life. In-person interviews were conducted with 2056 United States and Canadian residents selected at random. Subjects reported frequency and severity for 11 symptoms, prescription and over-the-counter medication use, primary care and specialty physician visits in prior three months, and completed the Psychological General Well-Being Scale. For analyses, subjects were classified into four mutually exclusive symptom groups: gastroesophageal reflux disease (GERD) -like, GERD plus motility-like (GERD+), ulcerlike, and motility-like. Of the total sample, 51.4% reported the occurrence of at least one UGIS in the prior three months. Subjects in the GERD+ and ulcer groups used more prescription medications and were more likely to see a physician about the symptoms (P < 0.001). Subjects with symptoms demonstrated poorer quality of life compared to subjects with no symptoms. The prevalence of UGIS in the general population is high and symptoms are associated with significant health-care utilization and poorer quality of life.

gastrointestinal symptomsulcergastroesophageal reflux diseasehealth-care utilizationquality of life

Copyright information

© Plenum Publishing Corporation 2000