Abstract
Objective: To measure recent changes in prostate-cancer mortality across 24 developed countries.
Methods: Mortality data for men aged 50–79 years were obtained from the World Health Organisation mortality database and we assessed trends in age-standardised mortality rates using joinpoint regression models.
Results: Significant reductions in prostate-cancer mortality were observed in United Kingdom, United States, Austria, Canada, Italy, France, Germany, Australia and Spain, and downward trends were also observable in the Netherlands, Ireland and Sweden.
Conclusions: Mortality declines for prostate cancer are now evident in 12 out of the 24 developed countries considered in this analysis. Increases in PSA screening and better treatment of early-stage disease, possibly acting in combination, remain plausible hypotheses.
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Baade, P., Coory, M. & Aitken, J. International Trends in Prostate-Cancer Mortality: The Decrease is Continuing and Spreading. Cancer Causes Control 15, 237–241 (2004). https://doi.org/10.1023/B:CACO.0000024212.66334.26
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DOI: https://doi.org/10.1023/B:CACO.0000024212.66334.26