Skip to main content
Log in

Exploring the relationships between intestinal microflora and inflammatory conditions of the human bowel and spine

  • Published:
Antonie van Leeuwenhoek Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Altschul SF, Gish W, Miller W, Myers EW & Lipman DJ (1990) Basic local alignment search tool. J. Mol. Biol. 215: 403–410.

    Article  PubMed  CAS  Google Scholar 

  • Beckwith CS, Franklin CL, Hook RR, Besch-Williford CL & Riley LK (1997) Fecal PCR assay for diagnosis of Helicobacter infection in laboratory rodents. J. Clin. Microbiol. 35: 1620–1623.

    PubMed  CAS  Google Scholar 

  • Berg DJ, Davidson N & Kuhn R, et al. (1996) Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses. J. Clin. Invest. 98: 1010–1020.

    PubMed  CAS  Google Scholar 

  • Cahill RJ, Foltz CJ, Fox JG, Dangler CA, Powrie F & Schauer DB (1997) Inflammatory bowel disease: an immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus. Infect. Immun. 65: 3126–3131.

    PubMed  CAS  Google Scholar 

  • Chadwick VS & Chen W (1999) The intestinal microflora and inflammatory bowel disease. In: Tannock GW (Ed) Medical Importance of the Normal Microflora pp 177–221. Kluwer Academic Publishers, Dordrecht.

    Google Scholar 

  • D'Andrea A, Aste-Amezaga M, Valiante NM, Ma X, Kubin M & Trinchieri G (1993) Interleukin-10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178: 1041–1048.

    Article  PubMed  Google Scholar 

  • De Keyser F, Elewaut D & De Vos M et al. (1998) Bowel inflammation and the spondyloarthropathies. Rheum. Dis. Clin. North Am. 24: 785–813.

    Article  PubMed  CAS  Google Scholar 

  • Deplancke B, Hristova KR & Oakley HA et al. (2000) Molecular ecological analysis of the succession and diversity of sulfatereducing bacteria in the mouse gastrointestinal tract. Appl. Environ. Microbiol. 66: 2166–2174.

    Article  PubMed  CAS  Google Scholar 

  • Drasar BS & Barrow PA (1985) Intestinal Microbiology. American Society for Microbiology, Washington, D.C.

    Google Scholar 

  • Drasar BS & Hill MJ (1974) Role of bacteria in the aetiology of cancer. In: Human Intestinal Flora pp 193–225. Academic Press, London.

    Google Scholar 

  • Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K & Meyer zum Buschenfelde K-H (1995) Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD). Clin. Exp. Immunol. 102: 448–455.

    Article  PubMed  CAS  Google Scholar 

  • Ebringer A (1983) The cross-tolerance hypothesis, HLA-B27 and ankylosing spondylitis. Br. J. Rheumatol. 22.

  • Elson CO, Sartor RB, Tennyson GS & Riddell RH (1995) Experimental models of inflammatory bowel disease. Gastroenterology 109: 1344–1367.

    Article  PubMed  CAS  Google Scholar 

  • Finegold SM & Sutter VL (1978) Fecal flora in different populations, with special reference to diet. Am. J. Clin. Nutr. 31: S116–S122.

    PubMed  CAS  Google Scholar 

  • Finegold SM, Sutter VL & Mathisen GE (1983) Normal indigenous intestinal flora. In: pp 3–31 Hentges DJ (Ed) Human Intestinal Microflora in Health and Disease. Academic Press, New York.

    Google Scholar 

  • Fox JG, Dewhirst FE, Fraser GJ, Paster BJ, Shames B & Murphy JC (1994) Intracellular Campylobacter-like organism from ferrets and hamsters with proliferative bowel disease is a Desulfovibrio sp. J. Clin. Microbiol. 32: 1229–1237.

    PubMed  CAS  Google Scholar 

  • Francois RJ, Eulderink F & Bywaters EG (1995) Commented glossary for rheumatic spinal diseases, based on pathology. Anna. Rheum. Dis. 54: 615–625.

    CAS  Google Scholar 

  • Franklin CL, Riley LK, Livingstone RS, Beckwith CS, Besch-Williford CL & Hook RR (1998) Enterohepatic lesions in SCID mice infected with Helicobacter bilis. Lab. Anim. Sci. 48: 334–339.

    PubMed  CAS  Google Scholar 

  • Franks AH, Harmsen HJ, Raangs GC, Jansen GJ, Schut F & Welling GW (1998) Variations of bacterial populations in human feces measured by fluorescent in situ hybridization with group-specific 16S rRNA-targeted oligonucleotide probes. Appl. Environ. Microbiol. 64: 3336–3345.

    PubMed  CAS  Google Scholar 

  • Fuller R (1989) Probiotics in man and animals. J. Appl. Bacteriol. 66: 365–378.

    PubMed  CAS  Google Scholar 

  • Gibson GR, Cummings JH & Macfarlane GT (1991) Growth and activities of sulphate-reducing bacteria in gut contents of healthy subjects and patients with ulcerative colitis. FEMS Microbiol. Ecol. 86: 103–112.

    Article  CAS  Google Scholar 

  • Goldin BR & Gorbach SL (1992) Probiotics for humans. In: Fuller R (Ed) Probiotics. The Scientific Basis pp 355–376. Chapman and Hall, London.

    Google Scholar 

  • Groux H, O'Garra A & Bigler M et al. (1997) A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389: 737–742.

    Article  PubMed  CAS  Google Scholar 

  • Haslock I (1973) Arthritis and Crohn's disease. A family study. Ann. Rheum. Dis. 32: 479–486.

    PubMed  CAS  Google Scholar 

  • Holdeman LV & Moore WE (1972) Roll-tube techniques for anaerobic bacteria. Am. J. Clin. Nutr. 25: 1314–1317.

    PubMed  CAS  Google Scholar 

  • Madsen KL, Doyle JS, Tavernini ME, Jewel LD, Rennie RP & GFedorak RN (2000) Antibiotic therapy attenuates colitis in interleukin-10 gene-deficient mice. Gastroenterology 118.

  • Matsuki T, Watanabe K, Tanaka R, Fukuda M & Oyaizu H (1999) Distribution of bifidobacterial species in human intestinal microflora examined with 16S rRNA-gene-targeted species-specific primers. Appl. Environ. Microbiol. 65: 4506–4512.

    PubMed  CAS  Google Scholar 

  • Metchnikoff E (1907) The Prolongation of Life. Optimistic Studies. William Heinemann, London.

    Google Scholar 

  • Metchnikoff E (1908) The Nature of Man. Studies in Optimistic Philosophy. William Heinemann, London.

    Google Scholar 

  • Mielants H, Veys EM & Cuvelier C, et al. (1995) The evolution of spondyloarthropathies in relation to gut histology. III. Relation between gut and joint. J. Rheum. 22: 2279–2284.

    PubMed  CAS  Google Scholar 

  • Moore WE, Cato EP & Holdeman LV (1978) Some current concepts in intestinal bacteriology. Am. J. Clin. Nutr. 31: S33–42.

    PubMed  CAS  Google Scholar 

  • Moore WE & Holdeman LV (1974) Special problems associated with the isolation and identification of intestinal bacteria in fecal flora studies. Am. J. Clin. Nutr. 27: 1450–1455.

    PubMed  CAS  Google Scholar 

  • Morrissey PJ, Charrier K, Braddy S, Liggitt D & Watson JD (1993) CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Cotransfer of purified CD4+ cells prevents disease development. J. Exp. Med. 178: 237–244.

    Article  PubMed  CAS  Google Scholar 

  • Muyzer G & Smalla K (1998) Application of denaturing gradient gel electrophoresis (DGGE) and temperature gradient gel electrophoresis (TGGE) in microbial ecology. Antonie Van Leeuwenhoek 73: 127–141.

    Article  PubMed  CAS  Google Scholar 

  • O'Sullivan DJ (1999) Methods of analysis of the intestinal microflora. In: Tannock GW (Ed) Probiotics: A Critical Review pp 23–44. Horizon Scientific Press., Wymondham, UK.

    Google Scholar 

  • Pitcher MC & Cummings JH (1996) Hydrogen sulphide: a bacterial toxin in ulcerative colitis? Gut 39: 1–4.

    PubMed  CAS  Google Scholar 

  • Rath HC, Bender DE & Holt LC et al. (1995) Metronidazole attenuates colitis in HLA-B27/b2 microglobulin transgenic rats: a pathogenic role for anaerobic bacteria. Clin. Immunol. Immunopathol. 76.

  • Rath HC, Herfath HH & Ikeda JS, et al. (1996) Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human B2 microglobulin transgenic rats. J. Clin. Invest. 98: 945–953.

    Article  PubMed  CAS  Google Scholar 

  • Rath HC, Schultz M & Dieleman LA, et al. (1998) Selective vs. broad spectrum antibiotics in the prevention and treatment of experimental colitis in two rodent models. Gastroenterology 114: A1067.

    Google Scholar 

  • Rath HC, Wilson KH & Sartor RB (1999) Differential induction of colitis and gastritis in HLA-B27 transgenic rats selectively colonized with Bacteroides vulgatus or Escherichia coli. Infect. Immun. 67: 2969–2969.

    PubMed  CAS  Google Scholar 

  • Sartor RB (1997) The influence of normal microbial flora on the development of chronic mucosal inflammation. Res. Immunol. 148: 567–576.

    Article  PubMed  CAS  Google Scholar 

  • Sartor RB, Rath HC, Lichtman SN & van Tol EA (1996) Animal models of intestinal and joint inflammation. Bailliere's Clin. Rheuma. 10: 55–76.

    Article  CAS  Google Scholar 

  • Sellon RK, Tonkonogy S & Schultz M et al. (1998) Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect. Immun. 66: 5224–5231.

    PubMed  CAS  Google Scholar 

  • Sghir A, Gramet G, Suau A, Rochet V, Pochart P & Dore J (2000) Quantification of bacterial groups within the human fecal flora by oligonucleotide probe hybridization. Appl. Environ. Microbiol. 66: 2263–2266.

    Article  PubMed  CAS  Google Scholar 

  • Suau A et al. (1999) Direct analysis of genes encoding 16S rRNA from complex communities reveals many novel molecular species within the human gut. Appl. Environ. Microbiol. 65: 4799–4807.

    PubMed  CAS  Google Scholar 

  • Tannock GW, Munro K, Harmsen HJM, Welling GW, Smart J & Gopal PK (2000) Analysis of the fecal microflora of human subjects consuming a probiotic containing Lactobacillus rhamnosus DR20. Appl. Environ. Microbiol. 66: 2578–2588.

    Article  PubMed  CAS  Google Scholar 

  • Tannock GW, Tilsala-Timisjarvi A, Rodtong S, Ng J, Munro K & Alatossava T (1999) Identification of Lactobacillus isolates from the gastrointestinal tract, silage, and yoghurt by 16S-23S rRNA gene intergenic spacer region sequence comparisons. Appl. Environ. Microbiol. 65: 4264–4267.

    PubMed  CAS  Google Scholar 

  • Taylor J & Parkes RJ (1985) Identifying different populations of sulphate-reducing bacteria within marine sediment systems, using fatty acid biomarkers. J. Microbiol. 131: 631–642.

    Article  CAS  Google Scholar 

  • Vaughan EE, Schut F, Heilig HGHJ, Zoetendal EG, De Vos WM & Akkermans ADL (2000) A molecular view of the intestinal ecosystem. Curr. Issues Intest. Microbiol. 1: 1–12.

    PubMed  CAS  Google Scholar 

  • Welling GW, Elfferich P, Raangs GC, Wildeboer-Veloo AC, Jansen GJ & Degener JE (1997) 16S ribosomal RNA-targeted oligonucleotide probes for monitoring of intestinal tract bacteria. Scand. J. Gastroenterol. 222: 17–19.

    CAS  Google Scholar 

  • Woese CR (1987) Bacterial evolution. Microbiol. Rev. 51: 221–271.

    PubMed  CAS  Google Scholar 

  • Zoetendal EG, Akkermans AD & De Vos WM (1998) Temperature gradient gel electrophoresis analysis of 16S rRNA from human fecal samples reveals stable and host-specific communities of active bacteria. Appl. Environ. Microbiol. 64: 3854–3859.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tannock, G.W. Exploring the relationships between intestinal microflora and inflammatory conditions of the human bowel and spine. Antonie Van Leeuwenhoek 81, 529–535 (2002). https://doi.org/10.1023/A:1020517603993

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1020517603993

Keywords

Navigation