Assessment of global and regional left ventricular function and volumes with 64-slice MSCT: A comparison with 2D echocardiography
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In patients with coronary artery disease (CAD), LV function and volumes are important parameters for long-term prognosis. Multislice computed tomography (MSCT) allows noninvasive assessment of the coronary arteries, but the accuracy of 64-slice MSCT for the assessment of left ventricular (LV) volumes and function is unknown.
Methods and Results
A head-to-head comparison between 64-slice MSCT and 2-dimensional (2D) echocardiography was performed in 40 patients with known or suspected CAD. The LV end-diastolic volume (LVEDV) and LV end-systolic volume (LVESV) were determined and the LV ejection fraction (LVEF) was derived. Regional wall motion was assessed visually using a 17-segment model. A 3-point scoring system was used to assign to each segment a wall motion score: 1 = normokinesia, 2 = hypokinesia, 3 = akinesia or dyskinesia. Two-dimensional echocardiography served as the gold standard. MSCT agreed well with 2D echocardiography for assessment of LVEDV (r = 0.97; p < .0001) and LVESV (r = 0.98; p < .0001). An excellent correlation between MSCT and 2D echocardiography was shown for the evaluation of LVEF (r = 0.91; p < .0001). Agreement for the assessment of regional wall motion was excellent (96%, κ = 0.82).
An accurate assessment of global and regional LV function and volumes is feasible with 64-slice MSCT.
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- Assessment of global and regional left ventricular function and volumes with 64-slice MSCT: A comparison with 2D echocardiography
Journal of Nuclear Cardiology
Volume 13, Issue 4 , pp 480-487
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Multislice computed tomography
- left ventricular function
- Industry Sectors
- Author Affiliations
- 1. Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
- 2. Leiden University Medical Center, Leiden, The Netherlands, Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands
- 3. Department of Radiology, Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands