Spectral deconvolution for overlapping GC/MS components

  • Bruce N. Colby

DOI: 10.1016/1044-0305(92)85033-G

Cite this article as:
Colby, B.N. J Am Soc Mass Spectrom (1992) 3: 558. doi:10.1016/1044-0305(92)85033-G


The use of mass chromatogram peak centroids has been investigated as a means of deconvoluting the spectra of overlapping gas chromatography/mass spectrometry components. The peak centroids have been calculated with a precision of 0.04 scans (sd). This proved sufficient to allow deconvolution of the mass spectra belonging to two chemical components which were eluted 0.48 scans apart. For a more complex chromatography peak, it was possible to deconvolute the spectra of six components which were eluted within a 9 scan window. All the spectra produced by using this deconvolution mechanism agreed well with National Institute of Standards and Technology database spectra.

Copyright information

© American Society for Mass Spectrometry 1992

Authors and Affiliations

  • Bruce N. Colby
    • 1
  1. 1.Paciftc Analytical, Inc.Carlsbad

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