, Volume 1472, Issue 1, p 11

Calcipotriol

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A 2-year-old boy developed exacerbation of atopic dermatitis (AD) during treatment with calcipotriol.

The boy, who had atopic dermatitis, presented with a severe flare of eczematous dermatitis on his face and scalp. His flare started within 24 hours of applying calcipotriol 0.005% cream and solution [dosage not stated] to AD sites due to a mistaken diagnosis of psoriasis. His flare, which was limited to the areas of calcipotriol application, progressed over 5 days of calcipotriol use.

The boy's calcipotriol was discontinued and he was treated with low-potency topical corticosteroids. His flare improved markedly within 72 hours.

Author comment: "In summary, our clinical findings suggest that [calcipotriol] can exacerbate a flare of AD."