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A retrospective review identified an 11-year-old girl who developed proteinuria while receiving topical cidofovir for the treatment of refractory warts [outcome not stated].
The girl had refractory verrucae on her hands and had been previously treated with salicylic acid and imiquimod. Cidofovir 1% cream was applied every other day for 6 weeks; concomitant medications included squaric acid dibutylester, cimetidine and imiquimod. After 5 weeks, a macroscopic urinalysis demonstrated 1+ albumin, and follow-up urinalysis showed trace protein thought to be consistent with postural proteinuria.
Author comment: "One child discontinued the medicine because a macroscopic urinalysis demonstrated 1+ albumin after 5 weeks. Follow-up urinalysis showed trace protein thought to be consistent with postural proteinuria."
- Gupta M, et al. Topical cidofovir for refractory verrucae in children. Pediatric Dermatology 30: 131-134, No. 1, Feb 2013. Available from: URL: http://dx.doi.org/10.1111/j.1525-1470.2012.01798.x - USA CrossRef
Volume 1458, Issue 1 , p 16
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