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Selecting the best device to deliver inhaled chronic obstructive pulmonary disease therapy in elderly patients requires an individualized approach

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Abstract

The prevalence of chronic obstructive pulmonary disease (COPD) increases with age. Elderly patients pose unique challenges with regard to the use of devices to deliver inhaled bronchodilators and corticosteroids, the key pharmacological treatments for COPD. The management of COPD in elderly patients, therefore, should involve individualized treatment plans that take into account the patient- and device-related factors. Healthcare professionals must provide adequate training on different inhaler device techniques, with regular reassessment and, when necessary, retraining.

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References

  1. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2016. Bethesda: Global Initiative for Chronic Obstructive Lung Disease (GOLD); 2015.

  2. Lavorini F, Mannini C, Chellini E, et al. Optimising inhaled pharmacotherapy for elderly patients with chronic obstructive pulmonary disease: the importance of delivery devices. Drugs Aging. 2016;33(7):461–73.

    Article  CAS  PubMed  Google Scholar 

  3. Janssens JP. Aging of the respiratory system: impact on pulmonary function tests and adaptation to exertion. Clin Chest Med. 2005;26(3):469–72.

    Article  PubMed  Google Scholar 

  4. Thomas M, Price D, Chrystyn H, et al. Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control. BMC Pulm Med. 2009;9:1.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Dekhuijzen PN, Vincken W, Virchow JC, et al. Prescription of inhalers in asthma and COPD: towards a rational, rapid and effective approach. Respir Med. 2013;107(12):1817–21.

    Article  CAS  PubMed  Google Scholar 

  6. Barrons R, Pegram A, Borries A. Inhaler device selection: special considerations in elderly patients with chronic obstructive pulmonary disease. Am J Heal Pharm. 2011;68(13):1221–32.

    Article  CAS  Google Scholar 

  7. Göriş S, Taşci S, Elmali F. The effects of training on inhaler technique and quality of life in patients with COPD. J Aerosol Med Pulm Drug Deliv. 2013;26(6):336–44.

    Article  PubMed  Google Scholar 

  8. Fink JB, Rubin BK. Problems with inhaler use: a call for improved clinician and patient education. Respir Care. 2005;50(10):1360–74.

    PubMed  Google Scholar 

  9. Jolly GP, Mohan A, Guleria R, et al. Evaluation of metered dose inhaler use technique and response to educational training. Indian J Chest Dis Allied Sci. 2015;57(1):17–20.

    CAS  PubMed  Google Scholar 

  10. Ho SF, OMahony MS, Steward JA, et al. Inhaler technique in older people in the community. Age Ageing. 2004;33(2):185–8.

    Article  PubMed  Google Scholar 

  11. Laube BL, Janssens HM, de Jongh FHC, et al. European Respiratory Society; International Society for Aerosols in Medicine. What the pulmonary specialist should know about the new inhalation therapies. Eur Respir J. 2011;37(6):1308–31.

    Article  CAS  PubMed  Google Scholar 

  12. Acerbi D, Brambilla G, Kottakis I. Advances in asthma and COPD management: delivering CFC-free inhaled therapy using Modulite technology. Pulm Pharmacol Ther. 2007;20(3):290–303.

    Article  CAS  PubMed  Google Scholar 

  13. Dhillon S, Keating GM. Beclometasone dipropionate/formoterol: in an HFA-propelled pressurised metered-dose inhaler. Drugs. 2006;66(11):1475–83.

    Article  CAS  PubMed  Google Scholar 

  14. Lavorini F, Fontana GA. Targeting drugs to the lungs: effect of spacer device. Exp Opin Drug Deliv. 2009;6(1):91–102.

    Article  CAS  Google Scholar 

  15. Lenny J, Innes J, Crompton GK. Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. Respir Med. 2000;94:496–500.

    Article  Google Scholar 

  16. Molimard M, Raherison C, Lignot S, et al. Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care. J Aerosol Med. 2003;16(3):249–54.

    Article  CAS  PubMed  Google Scholar 

  17. Azouz W, Chrystyn H. Clarifying the dilemmas about inhalation techniques for dry powder inhalers: integrating science with clinical practice. Prim Care Respir J. 2012;21(2):208–13.

    Article  PubMed  Google Scholar 

  18. Chrystyn H, Small M, Milligan G, et al. Impact of patients’ satisfaction with their inhalers on treatment compliance and health status in COPD. Respir Med. 2014;108(2):358–65.

    Article  PubMed  Google Scholar 

  19. Newman S. Improving inhaler technique, adherence to therapy and the precision of dosing: major challenges for pulmonary drug delivery. Expert Opin Drug Deliv. 2014;11(3):365–78.

    Article  CAS  PubMed  Google Scholar 

  20. Dalby R, Spallek M, Voshaar T. A review of the development of Respimat soft mist inhaler. Int J Pharm. 2004;283(1–2):1–9.

    Article  CAS  PubMed  Google Scholar 

  21. Denyer J. Adaptive aerosol delivery in practice. Eur Respir Rev. 1997;7(6):388–9.

    Google Scholar 

  22. Dhand R. Nebulisers that use a vibrating mesh or plate with multiple apertures to generate aerosol. Respir Care. 2002;47(12):1406–16.

    PubMed  Google Scholar 

  23. Waldrep JC, Dhand R. Advanced nebulizer designs employing vibrating mesh/aperture plate technologies for aerosol generation. Curr Drug Deliv. 2008;5(2):114–9.

    Article  CAS  PubMed  Google Scholar 

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    The article was adapted from Drugs and Aging 2016;33(7):461–73 [2] by salaried employees of Adis/Springer and was not supported by any external funding.

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    Adis Medical Writers. Selecting the best device to deliver inhaled chronic obstructive pulmonary disease therapy in elderly patients requires an individualized approach. Drugs Ther Perspect 33, 119–123 (2017). https://doi.org/10.1007/s40267-017-0379-9

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