Abstract
Optimal management of chronic noncancer pain in paediatric patients requires a multidisciplinary approach, with medications forming an important part of therapy. There is limited clinical evidence to support the use of specific medications in children with chronic pain, with most drugs being used off-label.
References
Mathew E, Kim E, Goldschneider KR. Pharmacological treatment of chronic non-cancer pain in pediatric patients. Paediatr Drugs. 2014;16(6):457–71.
Grégoire MC, Finley GA. Drugs for chronic pain in children: a commentary on clinical practice and the absence of evidence. Pain Res Manag. 2013;18(1):47–50.
Palermo T, Eccleston C, Goldschneider K, et al. Assessment and management of children with chronic pain: a position statement from the American Pain Society. 2012. http://www.americanpainsociety.org/uploads/pdfs/aps12-pcp.pdf. Accessed 13 Jan 2015.
Powers SW, Kashikar-Zuck SM, Allen JR, et al. Cognitive behavioral therapy plus amitriptyline for chronic migraine in children and adolescents: a randomized clinical trial. JAMA. 2013;310(24):2622–30.
Kaminski A, Kamper A, Thaler K, et al. Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescents. Cochrane Database Syst Rev. 2011;7:CD008013.
Chou R, Ballantyne JC, Fanciullo GJ, et al. Research gaps on use of opioids for chronic noncancer pain: findings from a review of the evidence for an American Pain Society and American Academy of Pain Medicine clinical practice guideline. J Pain. 2009;10(2):147–59.
Rose JB, Finkel JC, Arquedas-Mohs A, et al. Oral tramadol for the treatment of pain of 7–30 days’ duration in children. Anesth Analg. 2003;96(1):78–81.
Titchen T, Cranswick N, Beggs S. Adverse drug reactions to nonsteroidal anti-inflammatory drugs, COX-2 inhibitors and paracetamol in a paediatric hospital. Br J Clin Pharmacol. 2005;59(6):718–23.
Derry S, Moore RA, Rabbie R. Topical NSAIDs for chronic musculoskeletal pain in adults. Cochrane Database Syst Rev. 2012;9:CD007400.
Hoffert MJ, Couch JR, Diamond S, et al. Transnasal butorphanol in the treatment of acute migraine. Headache. 1995;35(2):65–9.
Kline RM, Kline JJ, Di Palma J, et al. Enteric-coated, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children. J Pediatr. 2001;138(1):125–8.
Hershey AD, Powers SW, Vockell AL, et al. Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine. Headache. 2007;47(1):73–80.
Slater SK, Nelson TD, Kabbouche MA, et al. A randomized, double-blinded, placebo-controlled, crossover, add-on study of coenzyme Q10 in the prevention of pediatric and adolescent migraine. Cephalalgia. 2011;31(8):897–905.
Wang F, Van Den Eeden SK, Ackerson LM, et al. Oral magnesium oxide prophylaxis of frequent migrainous headache in children: a randomized, double-blind, placebo-controlled trial. Headache. 2003;43(6):601–10.
Disclosure
This article was adapted from Pediatric Drugs 2014; 16(6):457–71 [1] by salaried/contracted employees of Adis/Springer. The preparation of this article was not supported by any external funding.
Author information
Authors and Affiliations
Consortia
Rights and permissions
About this article
Cite this article
Adis Medical Writers. Take a multidisciplinary approach when managing chronic noncancer pain in paediatric patients. Drugs Ther Perspect 31, 157–160 (2015). https://doi.org/10.1007/s40267-015-0201-5
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40267-015-0201-5