First reports of serious adverse drug reactions in recent weeks

Table 1 contains an overview of first published case reports of serious adverse drug reactions identified in the international literature in recent weeks by the drug safety alerting service Reactions Weekly. An event is serious (US FDA MedWatch definition) when the patient outcome is death, life threatening, hospitalization, disability, congenital anomaly or requires intervention to prevent permanent impairment or damage. Reactions and the customized Reactions Pharmacovigilance Service are produced by Adis, and monitor >4,000 journals, including relevant MEDLINE- and EMBASE-indexed journals, as well as companion journal supplements, major scientific meetings, the newsletters from the >80 national centres participating in the WHO International Drug Monitoring Programme, media releases, pharmaceutical company websites, and regulatory agency websites.

Table 1 First published reports of serious adverse drug reactions recently identified by Reactions Weekly