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Evaluating Outcomes for Older Patients with Parkinson’s Disease or Dementia with Lewy Bodies who have been Hospitalised for Hip Fracture Surgery: Potential Impact of Drug Administration

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Abstract

Introduction

People with Parkinson’s disease (PD) are at risk of falling and have an increased risk of complications and prolonged recovery during hospitalisation.

Objective

The aim of this study was to investigate the rate of complications and recovery related to a hip fracture in patients with PD.

Methods

All patients with PD or dementia with Lewy bodies (DLB) and a hip fracture who were admitted from January 2013 through June 2014 (18 months) to the Department of Orthopaedics, Copenhagen University Hospital, Herlev, Denmark were evaluated. Data regarding duration of admission, complications, timing of administration of anti-PD medication, and level of mobility at discharge were obtained from files of patients with PD or DLB and compared with data from a comparable group of patients who were admitted with a hip fracture and chronic obstructive pulmonary disease (COPD).

Results

A total of 31 patients with PD or DLB (PD/DLB group) and 45 patients with COPD (COPD group) were registered during the timeframe investigated. The patients in the PD/DLB group were significantly (p < 0.05) younger than those in the COPD group (77.7 vs. 80.7 years, respectively) and had lower co-morbidity scores (0.9 vs 2.6, respectively). There were no significant differences in length of stay, delirium, or number of infections between the groups. Two thirds of patients with PD were not able to walk unassisted at discharge. Less than 50% of anti-PD medication was given within ±1 h of the scheduled time.

Conclusions

Although patients with PD/DLB are significantly younger and have significantly lower degrees of co-morbidity than patients with COPD, their course and recovery after surgery are equivalent to those of patients with COPD. Patients with PD/DLB are at high risk of developing complications during hospital admission for hip fracture.

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Authors and Affiliations

  1. Department of Medicine and Geriatrics, Copenhagen University Hospital, Herlev, Denmark

    Marie Enemark & Mette Midttun

  2. Department of Neurology, Copenhagen University Hospital, Bispebjerg, Denmark

    Kristian Winge

  3. Fenrisgade 15th, 2200, Copenhagen N, Denmark

    Marie Enemark

Authors
  1. Marie Enemark
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  2. Mette Midttun
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  3. Kristian Winge
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Correspondence to Marie Enemark.

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Funding

No funding was received for the conduct of this study or preparation of the manuscript.

Conflict of interest

Marie Enemark, Mette Midttun and Kristian Winge have no financial, professional or personal conflicts of interest to declare.

Ethics approval

All relevant institutions (i.e. Datatilsynet, Denmark) have been informed of this study. It is not obligatory to notify additional institutions about quality studies in Denmark.

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Enemark, M., Midttun, M. & Winge, K. Evaluating Outcomes for Older Patients with Parkinson’s Disease or Dementia with Lewy Bodies who have been Hospitalised for Hip Fracture Surgery: Potential Impact of Drug Administration. Drugs Aging 34, 387–392 (2017). https://doi.org/10.1007/s40266-017-0454-x

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  • DOI: https://doi.org/10.1007/s40266-017-0454-x

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