Dear Reader

In this the final issue of Clinical Pharmacokinetics for 2014, the editors and production staff at Adis would like to take the opportunity to look back on all that has been achieved in the last 12 months and to thank the people who have given their time to ensure we continue to bring you world-class content.

We are pleased to advise you of a number of positive developments involving the Adis journals in 2014. This year saw the journal portfolio increase in size with the transfer of a number of existing Springer journals into the Adis portfolio, as well as the launch of two new open access titles: Drugs - Real World Outcomes targets research involving the use of real-world data to evaluate health outcomes and inform healthcare decision-making, with a particular focus on healthcare-related ‘big data’; and Drug Safety - Case Reports publishes reports of any unintended or adverse effects following administration of a medicinal product, as well as cases involving ‘near misses’ or a lack of efficacy.

The first six titles to be commissioned under the Adis Books programme will have been published by year end and we are developing a robust pipeline of new titles, involving top authors from around the globe. We have appreciated the many topical proposals submitted to date.

As another year draws to a close, we would like to say a big thank you to all the authors who have contributed articles to Clinical Pharmacokinetics. Without their expertise and hard work we would not have been able to publish the journal. The quality of published articles also reflects the significant time and effort put in by the peer reviewers, whose dedication ensures that we continue to publish content of the highest possible standard. In addition to the members of our Honorary Editorial Board, we would like to thank the following individuals who acted as reviewers for articles published in Clinical Pharmacokinetics in 2014:

Darrell R. Abernethy, USA

Mahmoud S. Ahmed, USA

Karel Allegaert, Belgium

Hesham S. Al-Sallami, New Zealand

Guohua An, USA

Peter Anderson, USA

Kristopher Attwood, USA

David J. Back, UK

Lorena Baietto, Italy

Joseph P. Balthasar, USA

Imke H. Bartelink, USA

Thomas J. Bateman, USA

Troels K. Bergmann, Denmark

Rajender K. Bhardwaj, USA

Robert R. Bies, USA

Francisco Blanco-Vaca, Spain

Arlin B. Blood, USA

Marta Boffito, UK

Davide Bolignano, Italy

Peter Bonate, USA

Olof Breuer, Sweden

Kim Brosen, Denmark

Richard C. Brundage, USA

Nuria B. Bruna, Spain

David M. Burger, The Netherlands

Andrea Calcagno, Italy

Bertrand Cariou, France

Mieke Carlier, Belgium

Dario Cattaneo, Italy

Etienne Chatelut, France

Shripad D. Chitnis, USA

Diana Chow, USA

Rene F. Chun, USA

James C. Cloyd, USA

Johan F. Coetzee, South Africa

Carol Collins, USA

John K. Darby, USA

Richard Day, Australia

Jose de Leon, USA

Saskia N. de Wildt, The Netherlands

Brenda C. M. de Winter, The Netherlands

Hans Denison, Sweden

Antonello Di Paolo, Italy

Michael Dolton, Australia

George L. Drusano, USA

Peter Edelbroek, The Netherlands

Douglas J. Eleveld, The Netherlands

Maurizio Fava, USA

Paolo Fogagnolo, Italy

Qiang Fu, USA

Salvador Fudio, Spain

Uwe Fuhr, Germany

Masahide Fukudo, Japan

Maria J. Garcia, Spain

Iain Gardner, UK

Leonid Gibiansky, USA

Brett C. Ginsburg, USA

Carlo B. Giorda, Italy

Magnus Gisslen, Sweden

Jennifer Goldman, USA

Kosalaram Goteti, USA

Navin Goyal, USA

Garry Graham, Australia

David J. Greenblatt, USA

Henk-Jan Guchelaar, The Netherlands

Amol Gupte, India

Walter E. Haefeli, Germany

Sebastian S. Harder, Germany

Sam Harirforoosh, USA

Manuel Haschke, Switzerland

Moustapha Hassan, Sweden

Robert P. Heaney, USA

Tycho Heimbach, USA

Anders Hellden, Sweden

Georg Hempel, Germany

Craig W. Hendrix, USA

Eva-Luise Hobl, Austria

Nicolas Hohmann, Germany

Nicholas H. G. Holford, New Zealand

Brett Howell, USA

Alwin D. R. Huitema, The Netherlands

Selwyn J. Hurwitz, USA

Angela Huttner, Switzerland

Yushi Inoue, Japan

Kaori Ito, USA

Kunihiko Itoh, Japan

Martin Jönsson, Sweden

Evelyne Jacqz-Aigrain, France

Janattul Ain Jamal, Australia

Masoud Jamei, UK

Philip E. James, UK

Michael W. Jann, USA

Petra M. Jauslin, Belgium

Zheng Jiao, China

Vincent Jullien, France

Anders E. Junker, Denmark

William J. Jusko, USA

Thomas Kakuda, USA

Gregory L. Kearns, USA

Ron Keizer, Sweden

Tatiana Khariton, USA

Min-Gul Kim, Republic of Korea

Jennifer J. Kiser, USA

Istvan Kiss, Hungary

Catherijne A. Knibbe, The Netherlands

Brigit Koch, The Netherlands

Nikolaos Kokras, Greece

Jill M. Kolesar, USA

Remco Koster, The Netherlands

John M. Kovarik, Switzerland

Stephanie Läer, Germany

Cornelia B. Landersdorfer, Australia

Hans H. Lennernas, Sweden

Juan J. L. Lertora, USA

Dominique Leveque, France

Senshang Lin, USA

Jeffrey Lipman, Australia

Yu-Li Liu, Taiwan, Republic of China

Wie Lu, China

Jorg Mørland, Norway

Iain A. M. MacPhee, UK

Joyce Macwan, USA

Rajanikanth Madabushi, USA

Iftekhar Mahmood, USA

John S. Markowitz, USA

Amélie Marsot, France

Ron A. A. Mathot, The Netherlands

Yuya Matsue, Japan

Munehide Matsuhisa, Japan

Massimo Carlo, Mauri, Italy

Jean-Xavier Mazoit, France

Jeannine McCune, USA

Andrew J. McLachlan, Australia

Murad R. Melhem, USA

Jasmina R. Milovanovic, Serbia

Phillip B. Mitchell, Australia

Ahmed N. Mohamed, Qatar

Jose Molto, Spain

David E. Moody, USA

Noppawan P. Morales, Thailand

Diane R. Mould, USA

Michael A. Nauck, Germany

Michael N. Neely, USA

Fahima Nekka, Canada

Laurent Nguyen, France

Thomas D. Nolin, USA

Michael T. Nurmohamed, The Netherlands

Koyode Ogungbenro, UK

Klaus T. Olkkola, Finland

Amy B. Pai, USA

Dominic L. Palazzolo, USA

Neil Parrott, Switzerland

Kennerly K. S. Patrick, USA

Charles A. Peloquin, USA

Vidya Perera, USA

Henry Pertinez, UK

Sheila A. Peters, Sweden

Klas Petersson, Sweden

Emilio M. Pich, Switzerland

Italo Poggesi, Belgium

Robert Powell, China

Richard A. Preston, USA

Luciano Quaranta, Italy

Natella Y. Rakhmanina, USA

Michael D. Reed, USA

Mario B. Regazzi, Italy

David M. Reith, New Zealand

Jason A. Roberts, Australia

Jürgen J. V. Rockstroh, Germany

Keith A. Rodvold, USA

Staffan Rosenborg, Sweden

Annick Rousseau, France

Malcolm M. Rowland, UK

Sam Salman, Australia

Raul D. Santos, Brazil

Naoki Sato, Japan

André J. Scheen, Belgium

Stephan Schmidt, USA

Sven Schmiedl, Germany

Jennifer J. Schneider, Australia

Sorell Schwartz, USA

Ute Schwarz, Canada

Frederique S. Servin, France

Catherine M. T. Sherwin, USA

Nathawut Sibmooh, Thailand

Marco Siccardi, UK

Jan Snoeys, Italy

Edoardo Spina, Italy

Joseph F. Standing, UK

Joachim Stangier, Germany

Julia C. Stingl, Germany

Chris Stockmann, USA

Leo M. Stolk, The Netherlands

Christophe Stove, Belgium

Anne-Marie Taburet, France

Prue Talbot, USA

Kazunari K. Tanabe, Japan

Joel Tarning, Thailand

Olli Tenhunen, Finland

Alison H. Thomson, UK

Giuseppe Toffoli, Italy

Sony Tuteja-Stevens, USA

Marta Vázquez, Uruguay

Teun Van Gelder, The Netherlands

Manthena V. Varma, USA

Gareth J. Veal, UK

Karthik Venkatakrishnan, UK

Alexander A. Vinks, USA

Jing Wang, USA

Carla Washington, USA

Kazuhito Watanabe, Japan

Michael Weiss, Germany

Kyle J. Wilby, Qatar

Katherine L. Wisner, USA

Daniel Wright, New Zealand

John W. Wright, USA

Yen Kuang Yang, Taiwan, Republic of China

Tsuyoshi Yokoi, Japan

Anne Zanchi, Switzerland

Markus Zeitlinger, Austria

Liping Zhang, USA

Ping Zhao, USA

Wie Zhao, France

Haojie Zhu, USA

We hope that you have found the articles published throughout 2014 to be both interesting and informative. The editors have appreciated the high quality of content contributed to the journal this year and look forward to keeping you up to date with topical issues in the field of clinical pharmacokinetics and pharmacodynamics in 2015.

With best wishes from the staff of Clinical Pharmacokinetics and all at Adis Publications.