Dear Reader,

As we approach the end of 2016, and publish our final issue of the American Journal of Cardiovascular Drugs for the year, we wish to reflect on another successful year for the journal and for others in the Adis Premier journals portfolio, and to thank all who have contributed to the American Journal of Cardiovascular Drugs over the past 12 months.

This year the American Journal of Cardiovascular Drugs published 41 manuscripts, including 23 review articles and 5 Adis Drug Evaluations, in 6 issues. The ten most popular articles published this year, based on the number of full-text downloads from Springer Link (as of October 2016), are listed below:

The Different Therapeutic Choices with ARBs. Which One to Give? When? Why?

Csaba András Dézsi

[http://link.springer.com/article/10.1007/s40256-016-0165-4]

Omega-3 Fatty Acid Formulations in Cardiovascular Disease: Dietary Supplements are Not Substitutes for Prescription Products

Jonathan Fialkow

[http://link.springer.com/article/10.1007/s40256-016-0170-7]

Addressing Major Unmet Needs in Patients with Systolic Heart Failure: The Role of Ivabradine

Antonio Carlos Pereira-Barretto

[http://link.springer.com/article/10.1007/s40256-016-0159-2]

Drug-Drug Interaction Studies of Cardiovascular Drugs Involving P-Glycoprotein, an Efflux Transporter, on the Pharmacokinetics of Edoxaban, an Oral Factor Xa Inhibitor

Jeanne Mendell, Hamim Zahir, Nobuko Matsushima, Robert Noveck, Frank Lee, Shuquan Chen, George Zhang, Minggao Shi

[http://link.springer.com/article/10.1007/s40256-013-0029-0]

Efficacy and Safety Study of Olmesartan Medoxomil, Amlodipine, and Hydrochlorothiazide Combination Therapy in Patients with Hypertension Not Controlled with Olmesartan Medoxomil and Hydrochlorothiazide Combination Therapy: Results of a Randomized, Double-Blind, Multicenter Trial

Il Suk Sohn, Chong-Jin Kim, Byung-Hee Oh, Taek-Jong Hong, Chang-Gyu Park, Byung-Soo Kim, Woo-Baek Chung

[http://link.springer.com/article/10.1007/s40256-015-0156-x]

A Systematic Review of Aspirin in Primary Prevention: Is It Time for a New Approach?

Carlos Brotons, Robert Benamouzig, Krzysztof J. Filipiak, Volker Limmroth, Claudio Borghi

[http://link.springer.com/article/10.1007/s40256-014-0100-5]

Pharmacokinetics and Tolerability of the Novel Oral Prostacyclin IP Receptor Agonist Selexipag

Priska Kaufmann, Kaori Okubo, Shirin Bruderer, Tim Mant, Tetsuhiro Yamada, Jasper Dingemanse, Hideya Mukai

[http://link.springer.com/article/10.1007/s40256-015-0117-4]

Challenges and Treatment for Stroke Prophylaxis in Patients with Atrial Fibrillation in Mexico: A Review

Luis Alcocer

[http://link.springer.com/article/10.1007/s40256-016-0163-6]

Non-Vitamin K Antagonist Oral Anticoagulants: New Choices for Patient Management in Atrial Fibrillation

Walid Saliba

[http://link.springer.com/article/10.1007/s40256-015-0124-5]

Serelaxin: A Novel Therapy for Acute Heart Failure with a Range of Hemodynamic and Non-Hemodynamic Actions

Javier Diez

[http://link.springer.com/article/10.1007/s40256-014-0069-0]

We offer our sincere thanks to all authors who have contributed articles to the American Journal of Cardiovascular Drugs over the course of 2016. Their skill and dedication are critical to the continued publication of the journal.

Mid-2016 saw the release of the ISI Journal Citation Reports and the latest journal impact factors. The Impact Factor of the American Journal of Cardiovascular Drugs fell marginally (~7%) from 2014 to 2.233, and the journal is currently ranked 61 of 124 journals in the ‘Cardiac & Cardiovascular System’ category. The majority of our other journals saw a rise in impact factor against the previous year. Most notably, five of our journals saw an increase of over 10% in impact factor—The Patient (17.08%), Clinical Drug Investigation (15.99%), the American Journal of Clinical Dermatology (13.17%), Drug Safety (13.52%), and Drugs (12.43%).

Another important milestone was reached for our recently launched open access journals, Drug Safety—Case Reports and Drugs—Real World Outcomes. Content from these journals is now available on PubMed Central.

The Adis journals portfolio will expand in 2017, with the launch of PharmacoEconomics—Open. This new journal will be fully open access and will focus on the publication of applied research on the economic implications and health outcomes associated with drugs, devices and other healthcare interventions. It joins our other well respected health outcomes publications, PharmacoEconomics, Applied Health Economics and Health Policy, and The Patient: Patient-Centered Outcomes Research.

The quality of published articles is, similarly, testament to the significant efforts of the peer reviewers, whose commitment ensures that the journal’s content is held to the highest possible standard. We would like to thank the following individuals who acted as reviewers for the American Journal of Cardiovascular Drugs in the last 12 months:

Shiv K. Agarwal, USA

Vineet Ahuja, India

Lorenzo Alberio, Switzerland

Muaamar Al-Gobari, Switzerland

Dominick J. Angiolillo, USA

Anastasia L. Armbruster, USA

Wilbert S. Aronow, USA

Christian Asseburg, Sweden

Vasilios G. Athyros, Greece

Ekaterina V. Baranova, the Netherlands

Anthony A. Bavry, USA

Barbara A. Bentz, USA

Aleš Blinc, Slovenia

Dirk J. Blom, South Africa

Edimar A. Bocchi, Brazil

Barry A. Borlaug, USA

Kenneth M. Borow, USA

Sorin J. Brener, USA

Sebastiano Calandra, Italy

Bertrand Cariou, France

Mattias Carlstrom, Sweden

Guillaume Cayla, France

Wisit Cheungpasitporn, USA

Derek P.B. Chew, Australia

Chern-En Chiang, Taiwan

Gabriel Chodick, Israel

Jonathan D. Cicci, USA

Arrigo F.G. Cicero, Italy

Andrea Colli, Italy

James M. Cotton, UK

Bertrand Crozatier, France

Wei Cui, China

Timothy W. Cutler, USA

Michael H. Davidson, USA

Olivier S. Descamps, Belgium

Sandeep Devabhakthuni, USA

Thomas Dschietzig, Germany

Andre R. Duraes, Brazil

Martin H. Ellis, Israel

Phillip Erwin, USA

Jonathan Fialkow, USA

Sebastien Foulquier, the Netherlands

Lutz Frankenstein, Germany

Freja S. Gaborit, Denmark

Thomas D. Giles, USA

Ornella Guardamagna, Italy

Job Harenberg, Germany

Derek J. Hausenloy, Singapore

Timothy D. Henry, USA

Inmaculada Hernandez, USA

Daniel E. Hilleman, USA

Hirofumi Hioki, Japan

Patrick Honoré, Belgium

Enyu Imai, Japan

Simon Jones, UK

Peter G. Jørgensen, Denmark

Parijat S. Joy, USA

Jayant K. Kairi, India

Waasil Kareem, USA

Swapna U. Karkare, USA

Lucas M. Kimmig, USA

Sverre E. Kjeldsen, Norway

Gerhard M. Kostner, Austria

David M. Kwiatkowski, USA

Irene M. Lang, Austria

Peter Lansberg, the Netherlands

Francesco Lapi, Italy

Kwan S. Lee, USA

Chung-Yi Li, Taiwan

Jian-Jun Li, China

Danny Liew, Australia

Tsung-Hua Lin, USA

Jou-Wei Lin, Taiwan

Charles E. Mahan, USA

Ahmed N. Mahmoud, USA

Arduino A. Mangoni, Australia

Jacques Mansourati, France

Maurizio Margaglione, Italy

Pedro Marques da Silva, Portugal

Carlos Martinez, Germany

Luca Mascitelli, Italy

Richard P. Mason, USA

John A. McClung, USA

Marco Metra, Italy

Toru Miyoshi, Japan

Ajit S. Mullasari, India

Sajan J.S. Nagpal, USA

Eliano P. Navarese, Italy

Wilmer W. Nichols, USA

Barbara Nussbaumer, Austria

Leiv Ose, Norway

Marlies Ostermann, UK

Siva K. Panguluri, USA

Előd Papp, Hungary

Akhil Parashar, USA

Alan R. Parrish, USA

Nishith N. Patel, UK

Paola Patrignani, Italy

Gregory M. Peterson, Australia

Mario Petretta, Italy

Sven Poli, Germany

Daniel J. Quinlan, UK

Yogesh N. Reddy, USA

Zeljko Reiner, Croatia

Anna Remková, Slovakia

Janine E. Roeters van Lennep, the Netherlands

Leonardo Roever, Brazil

Emilio Ros, Spain

Giuseppe M.C. Rosano, UK

Eli M. Roth, USA

Francois Roubille, France

Lewis J. Rubin, USA

Filippo M. Sarullo, Italy

Jennifer Simon, USA

Olivier Sitbon, France

Pil Sang S. Song, Republic of Korea

Geraud Souteyrand, France

Alessandro Squizzato, Italy

Isao Taguchi, Japan

Jose E. Tanus-Santos, USA

Costas G. Thomopoulos, Greece

Nidhish Tiwari, USA

Jay H. Traverse, USA

Bruno Trimarco, Italy

Kenichi Tsujita, Japan

Kengo Tsukahara, Japan

Per O. Vandvik, Norway

Monica Verdoia, Italy

Francesco Violi, Italy

Joan Vlayen, Belgium

Bernard Vrijens, Belgium

Amy Z. Wang, USA

Amanda Wang, Australia

Ralph-Steven Wedemeyer, Germany

Robert B. Wilson, Australia

James M. Wright, Canada

Yong Zhan, USA

Zugui Zhang, USA

Xin-Lin Zhang, China

In addition, we would like to thank the members of the journal’s Honorary Editorial Board, who have acted as peer reviewers and authors, and have provided guidance on journal content, policy and processes:

A. Michael Lincoff, USA [Consulting Editor]

Balram Bhargava, India

Deepak L. Bhatt, USA

John P. Cooke, USA

Prakash C. Deedwania, USA

Naranjan S. Dhalla, Canada

Phillip Erwin, USA

Arthur M. Feldman, USA

Valentin V. Fuster, USA

Xavier Girerd, France

Sidney Goldstein, USA

Joseph A. Hill, USA

Gowraganahalli Jagadeesh, USA

Neal S. Kleiman, USA

Antoine Lafont, France

Thierry H. Le Jemtel, USA

Frans H.H. Leenen, Canada

Mario Marzilli, Italy

Venu Menon, USA

Gilles Montalescot, France

Stephen J. Nicholls, Australia

Ali Oto, Turkey

Bertram Pitt, USA

Silvia G. Priori, Italy

C. Venkata S. Ram, USA

Gianpaolo Reboldi, Italy

Johanne Silvain, France

Kewal K. Talwar, India

Michal Tendera, Poland

Udho Thadani, USA

Alec Vahanian, France

George W. Vetrovec, USA

Michael A. Weber, USA

William S. Weintraub, USA

Harvey D. White, New Zealand

Nathan D. Wong, USA

We hope that you have found the articles published throughout 2016 to be both interesting and informative. We have appreciated the high quality of content contributed to the journal this year and we look forward to keeping you up to date with topical issues in the field of cardiovascular therapeutics in 2017.

With best wishes,

Amitabh Prakash

Editor, American Journal of Cardiovascular Drugs