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Surgical Management of SJS Sequelae: Outcomes and Alternatives

  • Ocular Prosthesis (J. de la Cruz, Section Editor)
  • Published:
Current Ophthalmology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

To enumerate and discuss the surgical options available for management of long term ocular sequelae of Stevens–Johnson syndrome (SJS).

Recent Findings

Amniotic membrane application for appropriately chosen cases in acute SJS may have a beneficial effect in the long term. Improvements continue to be made in both cell based therapy and keratoprosthesis design, improving outcomes when used for visual improvement in chronic cases of SJS.

Summary

Stevens–Johnson syndrome can have devastating chronic cicatrizing consequences for the ocular surface. Appropriate acute phase management as well as use of adjunctive measures, such as lid margin mucous membrane grafting and scleral lenses, can minimize the need for more complex surgery. Cell-based therapies, such as allogeneic limbal stem cell transplantation and cultivated oral mucosal epithelial transplantation, as well as various keratoprosthetic devices, such as the modified osteo-odonto-keratoprosthesis, the Boston keratoprosthesis types 1 and 2, and the LVP Kpro, provide options for vision improvement in different situations.

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Correspondence to Virender S. Sangwan.

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Jayesh Vazirani and Virender Sangwan declare no conflict of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical collection on Ocular Prosthesis.

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Vazirani, J., Sangwan, V.S. Surgical Management of SJS Sequelae: Outcomes and Alternatives. Curr Ophthalmol Rep 4, 213–219 (2016). https://doi.org/10.1007/s40135-016-0109-9

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  • DOI: https://doi.org/10.1007/s40135-016-0109-9

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