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Comparison of influenza and RSV diagnostic from nasopharyngeal swabs by rapid fluorescent immunoassay (Sofia system) and rapid bedside testing (BinaxNOW) vs. conventional fluorescent immunoassay in a German university children’s hospital

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Abstract

The Sofia fluorescent immunoassay showed excellent sensitivity and specificity compared to conventional fluorescent immunoassay for Influenza A (Influenza B was not detected during the study period) and RSV in patients with suspected ILI (influenza-like illness). Thus the fast and easy-to-handle Sofia FIA leads to rapid and reliable diagnosis, which can be used by clinicians to avoid unnecessary antibiotic treatment and rapidly identify patients who need to be isolated upon hospital admission.

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Authors and Affiliations

  1. Division of Pediatric Infectious Diseases, Hauner Children’s Hospital, Ludwig-Maximilians-University Munich, Lindwurmstr. 4, 80337, Munich, Germany

    Anita L. Rack-Hoch, Gudrun Laniado & Johannes Hübner

Authors
  1. Anita L. Rack-Hoch
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  2. Gudrun Laniado
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  3. Johannes Hübner
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Correspondence to Anita L. Rack-Hoch.

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Conflict of interest

The authors received laboratory supply for Sofia testing and a financial grant from TECOmedical AG, Gewerbestrasse 10, 4450 Sissach, Switzerland.

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Rack-Hoch, A.L., Laniado, G. & Hübner, J. Comparison of influenza and RSV diagnostic from nasopharyngeal swabs by rapid fluorescent immunoassay (Sofia system) and rapid bedside testing (BinaxNOW) vs. conventional fluorescent immunoassay in a German university children’s hospital. Infection 45, 529–532 (2017). https://doi.org/10.1007/s15010-017-1001-8

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  • DOI: https://doi.org/10.1007/s15010-017-1001-8

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