Abstract
Purpose
To develop recommendations for the management of acute hepatitis B by the Italian Society for the Study of Infectious and Tropical Diseases.
Methods
Development of the recommendations divided into three levels of evidence according to the GRADE system: A (high), B (medium) and C (low experts opinion), together with three recommendation levels: 1 (strong), 2 (medium), 3 (weak).
Results
The treatment with antivirals is in selected cases the mainstay of management of severe acute hepatitis, and should be started as a matter of urgency in order to prevent death.
Conclusions
These recommendations are meant to provide the rationale and practical indications for the management of acute hepatitis B (AHB).
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Acknowledgments
We would like to thank Dr.ssa Serena Cima for her excellent editing of the manuscript.
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The authors declare that there are no conflicts of interest.
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Contributors: R. Bruno, G. Carosi, N. Coppola, G. B. Gaeta, M. Puoti, T.Santantonio, G. Taliani, O. Armignacco, E. Sagnelli, M. Andreoni
Counsulting Committee: G. Angarano, G. Di Perri, G. D’Offizi, M. Galli, G. Rizzardini.
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Bruno, R., Carosi, G., Coppola, N. et al. Recommendations for the management of acute hepatitis B: position paper of the Italian Society for the Study of Infectious and Tropical Diseases (SIMIT). Infection 42, 811–815 (2014). https://doi.org/10.1007/s15010-014-0642-0
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DOI: https://doi.org/10.1007/s15010-014-0642-0