Infection

, Volume 41, Issue 1, pp 225–229

Transient reactivation of occult hepatitis B virus infection despite lamivudine prophylaxis in a patient treated for non-Hodgkin lymphoma

Authors

  • Gilda Tonziello
    • Department of Public Medicine, Section of Infectious DiseasesSecond University of Naples
  • Marintonietta Pisaturo
    • Department of Public Medicine, Section of Infectious DiseasesSecond University of Naples
  • Antonello Sica
    • Haematology UnitSecond University of Naples
  • Maria Giovanna Ferrara
    • Haematology UnitSecond University of Naples
  • Caterina Sagnelli
    • Department of Clinical and Experimental Medicine and Surgery “F Magrassi e A Lanzara”Second University of Naples
  • Giuseppe Pasquale
    • Department of Public Medicine, Section of Infectious DiseasesSecond University of Naples
    • Department of Public Medicine, Section of Infectious DiseasesSecond University of Naples
  • Salvatore Guastafierro
    • Haematology UnitSecond University of Naples
  • Nicola Coppola
    • Department of Public Medicine, Section of Infectious DiseasesSecond University of Naples
Case Report

DOI: 10.1007/s15010-012-0305-y

Cite this article as:
Tonziello, G., Pisaturo, M., Sica, A. et al. Infection (2013) 41: 225. doi:10.1007/s15010-012-0305-y

Abstract

A female patient with non-Hodgkin lymphoma who tested positive for surface antigen of the hepatitis B virus and negative for hepatitis B core antibody experienced a reactivation of occult HBV infection 20 months after rituximab discontinuation despite lamivudine prophylaxis covering the 4 months of rituximab administration and the subsequent 12 months.

Keywords

Occult HBV infection Rituximab Lamivudine prophylaxis Immunosuppressive diseases Onco-hematological diseases

Copyright information

© Springer-Verlag 2012