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Electrochemical sensing of D-penicillamine on modified glassy carbon electrode by using a nanocomposite of gold nanoparticles and reduced graphene oxide

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Abstract

A new electrochemical sensor was developed for determination of D-penicillamine using glassy carbon electrode which had been modified by gold nanoparticles–reduced graphene oxide nanocomposite (AuNPs/RGO/GCE) in aqueous solution. Cyclic voltammetry, transmission electron microscopy and electrochemical impedance spectroscopy were used for characterization of the modified electrode. The results indicated that the kinetic of oxidation reaction of D-penicillamine at the surface of the electrode was controlled by both diffusion and adsorption processes. In 0.1 mol L−1 phosphate buffer (pH 2.0), the oxidation current increased linearly with concentration of D-penicillamine with a linear range of 5.0 × 10−6 to 1.1 × 10−4 mol L−1 and regression coefficient of R 2 = 0.9972. Theoretical detection limit, defined based on 3σ of the blank signal (n = 9) divided by the slope of the linear regression equation, was 3.9 × 10−6 mol L−1 D-penicillamine using differential pulse voltammetry. The developed method was successfully applied to the determination of D-penicillamine in pharmaceutical formulation and blood serum samples.

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References

  1. F.E.O. Suliman, Z.H. Al-Lawati, S.M. Al-Kindy, J. Fluoresc. 18, 1131 (2008)

    Article  CAS  Google Scholar 

  2. M. Bieri, T. Bürgi, Langmuir 22, 8379 (2006)

    Article  CAS  Google Scholar 

  3. H. Kim, Y. Song, Rheumatol. Int. 17, 5 (1997)

    Article  CAS  Google Scholar 

  4. D. Joly, P. Rieu, A. Méjean, M.F. Gagnadoux, M. Daudon, P. Jungers, Pediatr. Nephrol. 13, 945 (1999)

    Article  CAS  Google Scholar 

  5. S. Gooneratne, D. Christensen, Vet. J. 153, 171 (1997)

    Article  CAS  Google Scholar 

  6. S. Cope-Yokoyama, M.J. Finegold, G.C. Sturniolo, K. Kim, C. Mescoli, M. Rugge, V. Medici, World J. Gastroenterol. 16, 1487 (2010)

    Article  CAS  Google Scholar 

  7. M. Yusof, R. Neal, N. Aykin, N. Ercal, Biomed. Chromatogr. 14, 535 (2000)

    Article  CAS  Google Scholar 

  8. F.E.O. Suliman, H.A. Al-Lawati, S.M. Al-Kindy, I.E.M. Nour, S.B. Salama, Talanta 61, 221 (2003)

    Article  CAS  Google Scholar 

  9. F.E.O. Suliman, M.M. Al-Hinai, S.M.Z. Al-Kindy, S.B. Salama, Talanta 74, 1256 (2008)

    Article  CAS  Google Scholar 

  10. X. Yang, H. Yuan, C. Wang, X. Su, L. Hu, D. Xiao, J. Pharm. Biomed. Anal. 45, 362 (2007)

    Article  CAS  Google Scholar 

  11. P. Taladriz-Blanco, N.J. Buurma, L. Rodriguez-Lorenzo, J. Perez-Juste, L.M. Liz-Marzan, P. Herves, J. Mater. Chem. 21, 16880 (2011)

    Article  CAS  Google Scholar 

  12. A.A. Torriero, H.D. Piola, N.A. Martínez, N.V. Panini, J. Raba, J.J. Silber, Talanta 71, 1198 (2007)

    Article  CAS  Google Scholar 

  13. A. Ghaffarinejad, F. Hashemi, Z. Nodehi, R. Salahandish, Bioelectrochemistry 99, 53 (2014)

    Article  CAS  Google Scholar 

  14. S. Zhang, W.L. Sun, W. Zhang, W.Y. Qi, L.T. Jin, K. Yamamoto, S. Tao, J. Jin, Anal. Chim. Acta 386, 21 (1999)

    Article  CAS  Google Scholar 

  15. S. Shahrokhian, A. Souri, H. Khajehsharifi, J. Electroanal. Chem. 565, 95 (2004)

    Article  CAS  Google Scholar 

  16. D. Saini, R. Chauhan, P.R. Solanki, T. Basu, ISRN Nanotechnol. 2012, 102543 (2012)

    Article  Google Scholar 

  17. C. Lee, X. Wei, J.W. Kysar, J. Hone, Science 321, 385 (2008)

    Article  CAS  Google Scholar 

  18. H. Razavi, S. Janfaza, Nanomed. J. 2, 74 (2015)

    CAS  Google Scholar 

  19. G. Doria, J. Conde, B. Veigas, L. Giestas, C. Almeida, M. Assunção, J. Rosa, P.V. Baptista, Sensors 12, 1657 (2012)

    Article  CAS  Google Scholar 

  20. Y. Fang, S. Guo, C. Zhu, Y. Zhai, E. Wang, Langmuir 26, 11277 (2010)

    Article  CAS  Google Scholar 

  21. Y. Xue, H. Zhao, Z. Wu, X. Li, Y. He, Z. Yuan, Biosens. Bioelectron. 29, 102 (2011)

    Article  CAS  Google Scholar 

  22. A. Wong, C.A. Razzino, T.A. Silva, O. Fatibello-Filho, Sens. Actuators B Chem. 231, 183 (2016)

    Article  CAS  Google Scholar 

  23. T. Chen, L. Tang, F. Yang, Q. Zhao, X. Jin, Y. Ning, G.J. Zhang, Anal. Lett. 49, 2223 (2016)

    Article  CAS  Google Scholar 

  24. Y. Zhu, D. Pan, X. Hu, H. Han, M. Lin, C. Wang, Sens. Actuators B Chem. 23, 1 (2017)

    Article  Google Scholar 

  25. M.L. Yola, T. Eren, N. Atar, Sens. Actuators B Chem. 210, 149 (2015)

    Article  CAS  Google Scholar 

  26. Y. Zhang, T.F. Kang, Y.W. Wan, S.Y. Chen, Microchim. Acta 165, 307 (2009)

    Article  CAS  Google Scholar 

  27. S.J. Li, D.H. Deng, Q. Shi, S.R. Liu, Microchim. Acta 177, 325 (2012)

    Article  CAS  Google Scholar 

  28. W.S. Hummers, R.E. Offeman, J. Am. Chem. Soc. 80, 1339 (1958)

    Article  CAS  Google Scholar 

  29. C. Fu, G. Zhao, H. Zhang, S. Li, Int. J. Electrochem. Sci. 8, 6269 (2013)

    CAS  Google Scholar 

  30. S. Verma, H.P. Mungse, N. Kumar, S. Choudhary, S.L. Jain, B. Sain, O.P. Khatri, Chem. Commun. 47, 12673 (2011)

    Article  CAS  Google Scholar 

  31. C. Wang, F. Ye, H. Wu, Y. Qian, Int. J. Electrochem. Sci. 8, 2440 (2013)

    CAS  Google Scholar 

  32. W. Feng, C. Liu, S. Lu, C. Zhang, X. Zhu, Y. Liang, J. Nan, Microchim. Acta 181, 501 (2014)

    Article  CAS  Google Scholar 

  33. L.H. Wang, W.S. Huang, Sensors 12, 3562 (2012)

    Article  CAS  Google Scholar 

  34. A.J. Bard, L.R. Faulkner, Electrochemical Methods: Fundamentals and Applications, 2nd edn. (Wiley, New York, 1980), pp. 592–593

    Google Scholar 

  35. X. Mu, L. Qi, P. Dong, J. Qiao, J. Hou, Z. Nie, H. Ma, Biosens. Bioelectron. 49, 249 (2013)

    Article  CAS  Google Scholar 

  36. J.B. Raoof, R. Ojani, F. Chekin, J. Chem. Sci. 121, 1083 (2009)

    Article  CAS  Google Scholar 

  37. B.L. Li, J.H. Luo, H.Q. Luo, N.B. Li, Sens. Actuators B Chem. 186, 96 (2013)

    Article  CAS  Google Scholar 

  38. A. Salmanipour, M.A. Taher, H. Beitollahi, R. Hosseinzadeh, Mater. Sci. Eng. C 33, 3160 (2013)

    Article  CAS  Google Scholar 

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Acknowledgements

The authors wish to express their gratitude to Shiraz University Research Council for the support of this work.

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Authors and Affiliations

  1. Professor Massoumi Laboratory, Department of Chemistry, College of Sciences, Shiraz University, Shiraz, 71454, Iran

    Marzieh Jafari, Javad Tashkhourian & Ghodratollah Absalan

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  1. Marzieh Jafari
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  2. Javad Tashkhourian
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  3. Ghodratollah Absalan
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Correspondence to Javad Tashkhourian or Ghodratollah Absalan.

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Jafari, M., Tashkhourian, J. & Absalan, G. Electrochemical sensing of D-penicillamine on modified glassy carbon electrode by using a nanocomposite of gold nanoparticles and reduced graphene oxide. J IRAN CHEM SOC 14, 1253–1262 (2017). https://doi.org/10.1007/s13738-017-1076-2

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  • DOI: https://doi.org/10.1007/s13738-017-1076-2

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