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An efficient, one-pot synthesis of pyrido[2,3-d:6,5-d′]dipyrimidines using SBA-15-supported sulfonic acid nanocatalyst under solvent-free conditions

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Abstract

An acidic nanocatalyst SBA-15-SO3H with a high surface area and high acid content was readily synthesized, characterized, and effectively used in the synthesis of some new and known pyrido[2,3-d:6,5-d′]dipyrimidine derivatives by condensation reaction of 6-aminouracil and different aldehydes under solvent-free conditions. The catalyst was reused for 6 runs without significant loss of its activity. Short reaction times, high yield of the products, solvent-free conditions, and use of a robust and reusable catalyst are worthwhile advantages of the present method.

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Acknowledgments

The authors gratefully acknowledge the Research Council of K. N. Toosi University of Technology for partial financial support of this work.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, K. N. Toosi University of Technology, P.O Box 15875-4416, Tehran, Iran

    Shahnaz Rostamizadeh, Leili Tahershamsi & Negar Zekri

Authors
  1. Shahnaz Rostamizadeh
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  2. Leili Tahershamsi
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  3. Negar Zekri
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Correspondence to Shahnaz Rostamizadeh.

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Rostamizadeh, S., Tahershamsi, L. & Zekri, N. An efficient, one-pot synthesis of pyrido[2,3-d:6,5-d′]dipyrimidines using SBA-15-supported sulfonic acid nanocatalyst under solvent-free conditions. J IRAN CHEM SOC 12, 1381–1389 (2015). https://doi.org/10.1007/s13738-015-0604-1

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