Abstract
A 78-year-old male was admitted to our hospital for treatment of multiple hepatic tumors, which were suspected as hepatic epithelioid hemangioendothelioma (HEHE) by percutaneous tumor needle biopsy. With a diagnosis of HEHE, the patient underwent hepatic resection. In pathological findings, the tumor was composed of numerous endothelial cells without epithelioid cells, and was diagnosed as hepatic angiosarcoma (HAS). The patient received percutaneous radiofrequency ablation for recurrent HAS at 5 and 25 months postoperatively, and remains well with recurrence as of 28 months after the primary hepatic resection. In spite of improvement in radiological imaging, preoperative differential diagnosis between HAS and other malignant vascular tumors of the liver is still difficult. We herein report a case of HAS mimicking HEHE, treated successfully.
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References
Molina E, Hernandez A (2003) Clinical manifestations of primary hepatic angiosarcoma. Dig Dis Sci 48(4):677–682
Yu RS, Chen Y, Jiang B, Wang LH, Xu XF (2008) Primary hepatic sarcomas: CT findings. Eur Radiol 18:2196–2205
Weitz J, Klimstra DS, Cymes K, Jarnagin WR, D’Angelica M, La Quaglia MP, Fong Y, Brennan MF, Blumgart LH, Dematteo RP (2007) Management of primary liver sarcomas. Cancer 109(7):1391–1396
Groeschl RT, Miura JT, Oshima K, Gamblin TC, Turaga KK (2014) Does histology predict outcome for malignant vascular tumors of the liver? J Surg Oncol 109(5):483–486
Louagie YA, Gianello P, Kestens PJ, Bonbled F, Haot JG (1984) Vinylchloride induced hepatic angiosarcoma. Br J Surg. 71(4):322–323
Timaran CH, Grandas OH, Bell JL (2000) Hepatic angiosarcoma: long-term survival after complete surgical removal. Am Surg. 66(12):1153–1157
Ozden I, Bilge O, Erkan M, Cevikbaş U, Acarli K (2003) Five years and 4 months of recurrence-free survival in hepatic angiosarcoma. J Hepatob Pancreat Surg 10(3):250–252
Duan XF, Li Q (2012) Primary hepatic angiosarcoma: a retrospective analysis of 6 cases. J Dig Dis 13(7):381–385
Huang NC, Kuo YC, Chiang JC, Hung SY, Wang HM, Hung YM, Chang YT, Wann SR, Chang HT, Wang JS, Ho SY, Guo HR (2015) Hepatic angiosarcoma may have fair survival nowadays. Med (Baltimore) 94(19):e816
Lin YH, Lin CC, Concejero AM, Yong CC, Kuo FY, Wang CC (2015) Surgical experience of adult primary hepatic sarcomas. World J Surg Oncol 13:87
Lee SW, Song CY, Gi YH, Kang SB, Kim YS, Nam SW, Lee DS, Kim JO (2008) Hepatic angiosarcoma manifested as recurrent hemoperitoneum. World J Gastroenterol 14(18):2935–2938
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Shiba, H., Sakamoto, T., Iida, T. et al. Hepatic angiosarcoma mimicking hepatic epithelioid hemangioendothelioma: report of a case. Int Canc Conf J 6, 29–34 (2017). https://doi.org/10.1007/s13691-016-0268-4
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DOI: https://doi.org/10.1007/s13691-016-0268-4