Natural Products and Bioprospecting

, Volume 2, Issue 4, pp 145–149

Five new mexicanolide type limonoids from Heynea trijuga

Open AccessRegular Article

DOI: 10.1007/s13659-012-0040-1

Cite this article as:
Yang, W., Kong, LM., Li, SF. et al. Nat. Prod. Bioprospect. (2012) 2: 145. doi:10.1007/s13659-012-0040-1

Abstract

Five new mexicanolide-type limonoids, heytrijunolides A–E (1–5) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compound 3 showed weak cytotoxicity against HL-60, SMMC-7721 and A-549 human tumor cell lines with the IC50 values of 21.88, 20.66 and 12.70 µM, respectively.
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Keywords

Heynea trijugaMeliaceaelimonoidsmexicanolide-typeheytrijunolide
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Supplementary material

13659_2012_40_MOESM1_ESM.pdf (4 mb)
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Copyright information

© The Author(s) 2012

This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.

Authors and Affiliations

  1. 1.State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of SciencesKunmingChina
  2. 2.Graduate University of Chinese Academy of SciencesBeijingChina