Open Access
Regular Article

Natural Products and Bioprospecting

, Volume 2, Issue 4, pp 145-149

Five new mexicanolide type limonoids from Heynea trijuga

Authors

  • Wei Yang
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences
    • Graduate University of Chinese Academy of Sciences
  • Ling-Mei Kong
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences
    • Graduate University of Chinese Academy of Sciences
  • Shi-Fei Li
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences
    • Graduate University of Chinese Academy of Sciences
  • Yan Li
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences
  • Yu Zhang
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences
  • Hong-Ping He
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences
  • Xiao-Jiang Hao
    • State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of BotanyChinese Academy of Sciences

DOI: 10.1007/s13659-012-0040-1

Abstract

Five new mexicanolide-type limonoids, heytrijunolides A–E (1–5) were isolated from the branches and leaves of Heynea trijuga. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis. Compound 3 showed weak cytotoxicity against HL-60, SMMC-7721 and A-549 human tumor cell lines with the IC50 values of 21.88, 20.66 and 12.70 µM, respectively.
https://static-content.springer.com/image/art%3A10.1007%2Fs13659-012-0040-1/MediaObjects/13659_2012_40_Fig1_HTML.gif

Keywords

Heynea trijuga Meliaceae limonoids mexicanolide-type heytrijunolide

Supplementary material

13659_2012_40_MOESM1_ESM.pdf (4 mb)
Supplementary material, approximately 3.98 MB.

Copyright information

© The Author(s) 2012