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Analysis of the brachial-ankle pulse wave velocity of stroke patients according to change of posture for healthy science research: A randomized controlled pilot trial

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Abstract

Brachial-ankle pulse wave velocity (BaPWV) in the as sessment of cardiovascular risk factors is often used to predict early cardiovascular disease, and it is used as a clinical indicator. A high value of BaPWV indicates high cardiovascular disorder. However, BaPWV and pressure waveforms after stroke are not fully understood in change of posture. Therefore, this study investigated the effects of BaPWV on posture changes in subjects. BaPWV was measured in twenty-eight subjects (sixteen healthy volunteers and twelve stroke patients) while they were in the body position such as supine, sitting, and standing posture. BaPWV was significantly increased in the stroke group compared with the healthy volunteers in supine and standing posture. BaPWV improved significantly in stroke patients of standing posture after the 4-week intervention program. Furthermore, analysis of the pressure waveforms of supine and standing posture showed that the peak pressure was significantly increased in the stroke group compared with the healthy group. The peak pressure of supine and standing posture on both the affected and non-affected sides was also significantly greater than in the healthy group. However, the rise and decay times were significantly decreased in the stroke group compared with the healthy group in supine and standing posture. The rise and decay time on both the affected and non-affected sides were significantly more decreased than in the control group. These results suggest that changed BaPWV and pulse waves are related with the pathologic states of stroke patients in various body postures.

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Kim, JH., Kim, J. Analysis of the brachial-ankle pulse wave velocity of stroke patients according to change of posture for healthy science research: A randomized controlled pilot trial. Toxicol. Environ. Health Sci. 7, 297–302 (2015). https://doi.org/10.1007/s13530-015-0252-y

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