Abstract
Hyperbranched polyglycidol is a biocompatible and biodegradable polymer used as a drug delivery system and emulsifier in the biomedical and food industry. This polymer is synthesized by ring-opening polymerization of glycidol using acids or Lewis bases as catalysts [1]. For biomedical applications, the presence of small traces of metallic catalysts in the body due may disastrous and dramatic problems. Therefore, rigorous and expensive purification methods were required to eliminate traces of catalyst from the polymer. In this work, we propose a new synthesis method to obtain polyglycidol using an Algerian montmorillonite clay [2], as catalyst. Finally we obtained a clean hyperbranched polyglycidol by simple filtration.
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El-Kebir, A., Harrane, A. & Belbachir, M. Protonated Montmorillonite Clay Used as Green Non-toxic Catalyst for the Synthesis of Biocompatible Polyglycidol. Arab J Sci Eng 41, 2179–2184 (2016). https://doi.org/10.1007/s13369-015-1862-z
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DOI: https://doi.org/10.1007/s13369-015-1862-z