Short Communication

Indian Pediatrics

, Volume 47, Issue 11, pp 959-963

First online:

Tolerance of baby cleansers in infants: A randomized controlled trial

  • Maria Victoria DizonAffiliated withUniversity of Santo Tomas HospitalDepartment of Dermatology, University of Santo Tomas Email author 
  • , Carlos GalzoteAffiliated withAsia-Pacific Skin Testing Centre
  • , Ricco EstanislaoAffiliated withJohnson & Johnson Pacific Pvt Ltd
  • , Noble MathewAffiliated withJohnson & Johnson Pacific Pvt Ltd
  • , Rashmi SarkarAffiliated withSafdarjung Hospital

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This randomized controlled trial was conducted to evaluate the tolerability of a new baby cleanser formulation — Johnson’s Top-to-Toe cleanser (JTT) on infantile skin. 180 healthy infants (60 in each group) were enrolled and JTT Sebamed Baby Liquid cleanser (SM), and lukewarm tap water were used on the skin of the subjects as whole body cleansers twice a week for 2 weeks. Assessment was done at baseline, 1 week and 2 weeks clinically by a dermato-logist, instrumentally, and by the parents. Clinical assessment (erythema, edema, dryness and scaling); skin moisture content; skin surface pH; trans-epidermal water loss; skin oxyhemoglobin and deoxyhemoglobin; and consu-mer satisfaction were the outcome measures. There was no significant erythema, edema, dryness, or scaling elicited by any of the three test components. Parents did not report any side-effects. All the three studied interventions used as whole body cleansers were efficacious and well tolerated by infants.

Key words

Baby cleanser Infant Moisture Tolerability Epidermal water loss Skin