Indian Pediatrics

, Volume 47, Issue 11, pp 959–963

Tolerance of baby cleansers in infants: A randomized controlled trial


    • University of Santo Tomas Hospital
    • Department of DermatologyUniversity of Santo Tomas
  • Carlos Galzote
    • Asia-Pacific Skin Testing Centre
  • Ricco Estanislao
    • Johnson & Johnson Pacific Pvt Ltd
  • Noble Mathew
    • Johnson & Johnson Pacific Pvt Ltd
  • Rashmi Sarkar
    • Safdarjung Hospital
Short Communication

DOI: 10.1007/s13312-010-0161-8

Cite this article as:
Dizon, M.V., Galzote, C., Estanislao, R. et al. Indian Pediatr (2010) 47: 959. doi:10.1007/s13312-010-0161-8


This randomized controlled trial was conducted to evaluate the tolerability of a new baby cleanser formulation — Johnson’s Top-to-Toe cleanser (JTT) on infantile skin. 180 healthy infants (60 in each group) were enrolled and JTT Sebamed Baby Liquid cleanser (SM), and lukewarm tap water were used on the skin of the subjects as whole body cleansers twice a week for 2 weeks. Assessment was done at baseline, 1 week and 2 weeks clinically by a dermato-logist, instrumentally, and by the parents. Clinical assessment (erythema, edema, dryness and scaling); skin moisture content; skin surface pH; trans-epidermal water loss; skin oxyhemoglobin and deoxyhemoglobin; and consu-mer satisfaction were the outcome measures. There was no significant erythema, edema, dryness, or scaling elicited by any of the three test components. Parents did not report any side-effects. All the three studied interventions used as whole body cleansers were efficacious and well tolerated by infants.

Key words

Baby cleanserInfantMoistureTolerabilityEpidermal water lossSkin

Copyright information

© Indian Academy of Pediatrics 2010