Review

Neurotherapeutics

, Volume 10, Issue 4, pp 709-721

Epigenetics of Alzheimer’s Disease and Frontotemporal Dementia

  • Chendhore S. VeerappanAffiliated withSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA Email author 
  • , Sama SleimanAffiliated withBurke Research Center, Weill Medical College of Cornell University
  • , Giovanni CoppolaAffiliated withSemel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLAProgram in Neurogenetics, Department of Neurology, David Geffen School of Medicine at UCLA

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Abstract

This article will review the recent advances in the understanding of the role of epigenetic modifications and the promise of future epigenetic therapy in neurodegenerative dementias, including Alzheimer’s disease and frontotemporal dementia.

Keywords

Neurodegeneration Epigenetics Alzheimer’s disease Frontotemporal dementia Epigenetic drugs Therapy