Neurotherapeutics

, Volume 10, Issue 4, pp 709–721

Epigenetics of Alzheimer’s Disease and Frontotemporal Dementia

  • Chendhore S. Veerappan
  • Sama Sleiman
  • Giovanni Coppola
Review

DOI: 10.1007/s13311-013-0219-0

Cite this article as:
Veerappan, C.S., Sleiman, S. & Coppola, G. Neurotherapeutics (2013) 10: 709. doi:10.1007/s13311-013-0219-0

Abstract

This article will review the recent advances in the understanding of the role of epigenetic modifications and the promise of future epigenetic therapy in neurodegenerative dementias, including Alzheimer’s disease and frontotemporal dementia.

Keywords

NeurodegenerationEpigeneticsAlzheimer’s diseaseFrontotemporal dementiaEpigenetic drugsTherapy

Supplementary material

13311_2013_219_MOESM1_ESM.pdf (1.2 mb)
ESM 1(PDF 1.19 MB)

Copyright information

© The American Society for Experimental NeuroTherapeutics, Inc. 2013

Authors and Affiliations

  • Chendhore S. Veerappan
    • 1
  • Sama Sleiman
    • 2
  • Giovanni Coppola
    • 1
    • 3
  1. 1.Semel Institute for Neuroscience and Human BehaviorDavid Geffen School of Medicine at UCLALos AngelesUSA
  2. 2.Burke Research CenterWeill Medical College of Cornell UniversityWhite PlainsUSA
  3. 3.Program in Neurogenetics, Department of NeurologyDavid Geffen School of Medicine at UCLALos AngelesUSA