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Note of the methodological flaws in the paper entitled “GSTT1 and GSTM1 polymorphisms predict treatment outcome for breast cancer: a systematic review and meta-analysis”

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Tumor Biology

The Original Article was published on 14 November 2015

Abstract

With great interest, we read the paper “GSTT1 and GSTM1 polymorphisms predict treatment outcome for breast cancer: a systematic review and meta-analysis” (by Hu XY et al.), which has reached important conclusions that GSTM1 null and GSTT1/GSTM1 double null polymorphisms might be significantly associated with an increased tumor response in breast cancer. The result is encouraging. Nevertheless, several methodological flaws in this meta-analysis are worth noticing.

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References

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Authors and Affiliations

  1. Department of Geriatrics, Second Xiangya Hospital, Central South University, No.139, Middle Renmin Road, Changsha, 410011, Hunan, China

    Mali Qiu, Xu Wu & Xiaobing Qu

Authors
  1. Mali Qiu
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  2. Xu Wu
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  3. Xiaobing Qu
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Correspondence to Xiaobing Qu.

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Qiu, M., Wu, X. & Qu, X. Note of the methodological flaws in the paper entitled “GSTT1 and GSTM1 polymorphisms predict treatment outcome for breast cancer: a systematic review and meta-analysis”. Tumor Biol. 37, 12897–12899 (2016). https://doi.org/10.1007/s13277-016-5154-3

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  • DOI: https://doi.org/10.1007/s13277-016-5154-3

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