Abstract
Korean native cattle, known as Hanwoo, have been raised in the Korean Peninsula since 2000 B.C. for use as a draft animal. However, Hanwoo now have an important position in the Korean livestock industry as a meat source. Therefore, the breeding and selection of Hanwoo are crucial for the industry. Although many researchers have studied the genetic architecture of Hanwoo, no well-established Hanwoo-related databases exist. In order to better understand the genetic contents of Hanwoo, an integrated database is necessary. We constructed a genetic variants database including annotation information. HanwooGDB (http://hanwoogdb.snu.ac.kr) provides genetic variants (SNPs, INDELs, CNVs) in the Hanwoo genome produced by Next Generation Sequencing data collected from 23 cattle. The identified SNPs were integrated with SNP chip data and annotation information for checking the concordance of position of each SNP and inferring functional aspects. This database provides browsers to understand and visualize the comprehensive information of these variants and allows users to download data according to their preference from this database without limitation. This database will contribute to genetic research and development of Hanwoo breeding strategies.
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Acknowledgments
This study was supported by grants from Research Program (Project No: PJ008487) of the National Livestock Research Institute and Next Generation BioGreen 21 Program (Project No: PJ008191 and PJ00995401) of Rural Development Administration, Republic of Korea.
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The authors declare that they have no competing interests.
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Kwondo Kim and Woori Kwak have contributed equally to this work.
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Kim, K., Kwak, W., Sung, SS. et al. A novel genetic variant database for Korean native cattle (Hanwoo): HanwooGDB. Genes Genom 37, 15–22 (2015). https://doi.org/10.1007/s13258-014-0224-7
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DOI: https://doi.org/10.1007/s13258-014-0224-7