Abstract
We report the development of a novel nonenzymatic glucose sensor based on single-walled carbon nanotube film electrodes coated with iridium nanoparticles (IrNPs-SWCNT). The SWCNT film electrode was first loaded with iridium nanoparticles (IrNPs) by an easily controllable chronocoulometry technique. The SWCNT film electrode coated with IrNPs was characterized by field emission scanning electron microscopy and electrochemical techniques like cyclic voltammetry (CV) and amperometry. There was no current response for glucose oxidation in neutral and acidic media, but a couple of oxidative and reductive peaks were observed when the IrNPs-SWCNT electrode was scanned in alkaline media, showing the strong electrocatalytic activity toward glucose oxidation. Amperometric measurements showed a high sensitivity of 63 μAcm−2 mM−1 and a detection limit of 17 μM; further, the measurements showed a linear range of 0.59–14 mM. To improve the selectivity of the electrode, the prepared IrNPs-SWCNT film electrode was coated using a 1.0% Nafion aqueous solution. When the electrodes were exposed to interfering substances such as uric acid and ascorbic acid, there were no significant signals observed from these substances, indicating that Nafion is an effective permselective polymer barrier. The sensitivity of the Nafion-coated electrode was 23 μAcm−2 mM−1 and the detection limit was 47 μM. In addition, the electro-catalytic activity of the Nafioncoated electrode was still stable after 50 cycles in the presence of a 3.0 mM glucose solution as measured by CV.
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References
Ye, J.-S. et al. Nonenzymatic glucose detection using multi-walled carbon nanotube electrodes. Electrochem. Commun. 6, 66–70 (2004).
Wang, J., Thomas, D.F. & Chen, A. Nonenzymatic Electrochemical Glucose Sensor Based on Nanoporous PtPb Networks. Anal. Chem. 80, 997–1004 (2008).
Holt-Hindle, P., Nigro, S., Asmussen, M. & Chen, A. Amperometric glucose sensor based on platinum-iridium nanomaterials. Electrochem. Commun. 10, 1438–1441 (2008).
Park, S., Boo, H. & Chung, T.D. Electrochemical nonenzymatic glucose sensors. Anal. Chim. Acta 556, 46–57 (2006).
Kwon, S.G. & Hyeon, T. Colloidal Chemical Synthesis and Formation Kinetics of Uniformly Sized Nanocrystals of Metals, Oxides, and Chalcogenides. Acc. Chem. Res. 41, 1696–1709 (2008).
Wilcoxon, J.P. & Abrams, B.L. Synthesis, structure and properties of metal nanoclusters. Chem. Soc. Rev. 35, 1162–1194 (2006).
Stoimenov, P.K., Klinger, R.L., Marchin, G.L. & Klabunde, K.J. Metal Oxide Nanoparticles as Bactericidal Agents. Langmuir 18, 6679–6686 (2002).
Mori, K. & Yamashita, H. Progress in design and architecture of metal nanoparticles for catalytic applications. Phys. Chem. Chem. Phys. 12, 14420–14432 (2010).
Welch, C. & Compton, R. The use of nanoparticles in electroanalysis: a review. Anal. Bioanal. Chem. 384, 601–619 (2006).
Katz, E., Willner, I. & Wang, J. Electroanalytical and Bioelectroanalytical Systems Based on Metal and Semiconductor Nanoparticles. Electroanal. 16, 19–44 (2004).
Wu, B., Kuang, Y., Zhang, X. & Chen, J. Noble metal nanoparticles/carbon nanotubes nanohybrids: Synthesis and applications. Nano Today 6, 75–90 (2011).
Kundu, S. & Liang, H. Shape-selective formation and characterization of catalytically active iridium nanoparticles. J. Colloid Interf. Sci. 354, 597–606 (2011).
Nakatsuji, T. Studies on the structural evolution of highly active Ir-based catalysts for the selective reduction of NO with reductants in oxidizing conditions. Appl. Catal. B-Environ 25, 163–179 (2000).
Nawdali, M., Iojoiu, E., Gélin, P., Praliaud, H. & Primet, M. Influence of the pre-treatment on the structure and reactivity of Ir/γ-Al2O3 catalysts in the selective reduction of nitric oxide by propene. Appl. Catal. AGeneral 220, 129–139 (2001).
Reyes, P., Rojas, H. & Fierro, J.L.G. Kinetic study of liquid-phase hydrogenation of citral over Ir/TiO2 catalysts. Appl. Catal. A-General 248, 59–65 (2003).
Reyes, P., Rojas, H., Pecchi, G. & Fierro, J.L.G. Liquid-phase hydrogenation of citral over Ir-supported catalysts. J. Mol. Catal. A-Chem. 179, 293–299 (2002).
Liu, G. & Zhang, H. Facile Synthesis of Carbon-Supported IrxSey Chalcogenide Nanoparticles and Their Electrocatalytic Activity for the Oxygen Reduction Reaction. J. Phys. Chem. C 112, 2058–2065 (2008).
Papageorgopoulos, D.C., Liu, F. & Conrad, O. Reprint of “A study of RhxSy/C and RuSex/C as methanol-tolerant oxygen reduction catalysts for mixed-reactant fuel cell applications”. Electrochim. Acta 53, 1037–1041 (2007).
Marshall, A., BØrresen, B., Hagen, G., Tsypkin, M. & Tunold, R. Electrochemical characterisation of IrxSn1-xO2 powders as oxygen evolution electrocatalysts. Electrochim. Acta 51, 3161–3167 (2006).
Colby, D.A., Bergman, R.G. & Ellman, J.A. Stereoselective Alkylation of α,β-Unsaturated Imines via CH Bond Activation. J. Am. Chem. Soc. 128, 5604–5605 (2006).
Tzschucke, C.C., Murphy, J.M. & Hartwig, J.F. Arenes to Anilines and Aryl Ethers by Sequential Iridium-Catalyzed Borylation and Copper-Catalyzed Coupling. Org. Lett. 9, 761–764 (2007).
Wong-Foy, A.G., Bhalla, G., Liu, X.Y. & Periana, R. A. Alkane C-H Activation and Catalysis by an ODonor Ligated Iridium Complex. J. Am. Chem. Soc. 125, 14292–14293 (2003).
Wang, J., Rivas, G. & Chicharro, M. Glucose microsensor based on electrochemical deposition of iridium and glucose oxidase onto carbon fiber electrodes. J. Electroanal. Chem. 439, 55–61 (1997).
Jhas, A.S., Elzanowska, H., Sebastian, B. & Birss, V. Dual oxygen and Ir oxide regeneration of glucose oxidase in nanostructured thin film glucose sensors. Electrochim. Acta 55, 7683–7689 (2010).
Shen, J., Dudik, L. & Liu, C.-C. An iridium nanoparticles dispersed carbon based thick film electrochemical biosensor and its application for a single use, disposable glucose biosensor. Sensor. Actuat. B-Chem 125, 106–113 (2007).
Rodríguez, M.C. & Rivas, G.A. Glucose Biosensor Prepared by the Deposition of Iridium and Glucose Oxidase on Glassy Carbon Transducer. Electroanal. 11, 558–564 (1999).
Fang, L., Li, W., Zhou, Y. & Liu, C.-C. A single-use, disposable iridium-modified electrochemical biosensor for fructosyl valine for the glycoslated hemoglobin detection. Sensor. Actuat. B-Chem. 137, 235–238 (2009).
Baughman, R.H., Zakhidov, A.A. & de Heer, W.A. Carbon Nanotubes-the Route Toward Applications. Science 297, 787–792 (2002).
Jacobs, C.B., Peairs, M.J. & Venton, B.J. Review: Carbon nanotube based electrochemical sensors for biomolecules. Anal. Chim. Acta 662, 105–127 (2010).
Wang, J. et al. Nonenzymatic Glucose Sensor Using Freestanding Single-Wall Carbon Nanotube Films. Electrochem. Solid-State Lett. 10, J58–J60 (2007).
Kang, X., Mai, Z., Zou, X., Cai, P. & Mo, J. A sensitive nonenzymatic glucose sensor in alkaline media with a copper nanocluster/multiwall carbon nanotubemodified glassy carbon electrode. Anal. Biochem. 363, 143–150 (2007).
Li, L.-H. & Zhang, W.-D. Preparation of carbon nanotubes supported platinum nanoparticles by an organic colloidal process for nonenzymatic glucose sensing. Microchim Acta 163, 305–311 (2008).
Cui, H.-F. et al. Selective and sensitive electrochemical detection of glucose in neutral solution using platinum-lead alloy nanoparticle/carbon nanotube nanocomposites. Anal. Chim. Acta 594, 175–183 (2007).
Xiao, F., Zhao, F., Mei, D., Mo, Z. & Zeng, B. Nonenzymatic glucose sensor based on ultrasonic-electrodeposition of bimetallic PtM (M=Ru, Pd and Au) nanoparticles on carbon nanotubes-ionic liquid composite film. Biosens. Bioelectron. 24, 3481–3486 (2009).
Pham, X.-H., Ngoc Bui, M.-P., Li, C.A., Han, K.N. & Seong, G.H. Electrochemical Patterning of Palladium Nanoparticles on a Single-Walled Carbon Nanotube Platform and Its Application to Glucose Detection. Electroanal. 23, 2087–2093 (2011).
Moore, C.M., Akers, N.L., Hill, A.D., Johnson, Z.C. & Minteer, S.D. Improving the Environment for Immobilized Dehydrogenase Enzymes by Modifying Nafion with Tetraalkylammonium Bromides. Biomacromolecules 5, 1241–1247 (2004).
Male, K.B., Hrapovic, S., Liu, Y., Wang, D. & Luong, J.H.T. Electrochemical detection of carbohydrates using copper nanoparticles and carbon nanotubes. Anal. Chim. Acta 516, 35–41 (2004).
Kong, B.-S., Jung, D.-H., Oh, S.-K., Han, C.-S. & Jung, H.-T. Single-Walled Carbon Nanotube Gold Nanohybrids: Application in Highly Effective Transparent and Conductive Films. J. Phys. Chem. C 111, 8377–8382 (2007).
Bui, M.-P.N. et al. Electrochemical patterning of gold nanoparticles on transparent single-walled carbon nanotube films. Chem. Commun. 5549–5551 (2009).
Ndamanisha, J.C. & Guo, L.P. Nonenzymatic glucose detection at ordered mesoporous carbon modified electrode. Bioelectrochem. 77, 60–63 (2009).
Zhou, Y.G., Yang, S., Qian, Q.Y. & Xia, X.H. Gold nanoparticles integrated in a nanotube array for electrochemical detection of glucose. Electrochem. Commun. 11, 216–219 (2009).
Li, Y., Song, Y.Y., Yang, C. & Xia, X.H. Hydrogen bubble dynamic template synthesis of porous gold for nonenzymatic electrochemical detection of glucose. Electrochem. Commun. 9, 981–988 (2007).
Park, S., Chung, T.D. & Kim, H.C. Nonenzymatic glucose detection using mesoporous platinum. Anal. Chem. 75, 3046–3049 (2003).
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Irfan, M., Pham, XH., Han, K.N. et al. Decoration of carbon nanotube films with iridium nanoparticles and their electrochemical characterization. BioChip J 8, 129–136 (2014). https://doi.org/10.1007/s13206-014-8208-x
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DOI: https://doi.org/10.1007/s13206-014-8208-x