Abstract
There are no published studies that have compared quality outcomes of hospitalized poisoned patients primarily under the care of physician medical toxicologists to patients treated by non-toxicologists. We hypothesized that inpatients primarily cared for by medical toxicologists would exhibit shorter lengths of stay (LOS), lower costs, and decreased mortality. Patients discharged in 2010 and 2011 from seven hospitals within the same health care system and greater metropolitan area with Medicare severity diagnosis-related groups for “poisoning and toxic effects of drugs” with and without major comorbidities or complications (917 & 918, respectively) were identified from a Premier® database. The database contained severity-weighted comparisons between expected and observed outcomes for each patient. Outcome parameters were differences between expected and observed LOS, cost, and percent mortality. These were then compared among groups of patients primarily admitted and cared for by (1) medical toxicologists at one hospital (Banner Good Samaritan Medical Center, BGS), (2) non-toxicologists at BGS, and (3) non-toxicologists at six other hospitals. Records of 3,581 patients contained complete data for assessment of at least one outcome measure. Patients cared for by medical toxicologists experienced favorable differences in LOS, costs, and mortality compared with other patient groups (p < 0.001). If patients cared for by non-toxicologists had experienced similar differences in observed over expected values for LOS, cost, and mortality as those cared for by medical toxicologists, there would have been a median savings of 1,483 hospital days, $4.269 million, and a significant decrease in mortality during the 2-year study period. Differences between observed and expected LOS, cost, and mortality in patients primarily cared for by medical toxicologists were significantly better than in patients cared for by non-toxicologists, regardless of facility. These data suggest that significant reductions in patient hospital days, costs, and mortality are possible when medical toxicologists directly care for hospitalized patients.
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References
Mowry JB, Spyker DA, Cantilena LR Jr, Bailey JE, Ford M (2013) 2012 annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 30th annual report. Clin Toxicol (Phila) 51(10):949–1229
Rabel BV (2012) Poisonings among Arizona residents, 2011. In: Arizona Department of Health Services. http://www.azdhs.gov/phs/owch/pdf/injuryprevention/poisonings-among-az-residents2011.pdf
Nelson LS, Baker BA, Osterhoudt KC, Snook CP, Keehbauch JN (2012) The 2012 core content of medical toxicology. J Med Toxicol 8(2):183–191
Wax PM, Donovan JW (2000) Fellowship training in medical toxicology: characteristics, perceptions, and career impact. J Toxicol Clin Toxicol 38(6):637–642, discussion 643–4
Blizzard JC, Michels JE, Richardson WH, Reeder CE, Schulz RM, Holstege CP (2008) Cost-benefit analysis of a regional poison center. Clin Toxicol (Phila) 46(5):450–456
Bunn TL, Slavova S, Spiller HA, Colvin J, Bathke A, Nicholson VJ (2008) The effect of poison control center consultation on accidental poisoning inpatient hospitalizations with preexisting medical conditions. J Toxicol Environ Health A 71(4):283–288
Friedman LS, Krajewski A, Vannoy E, Allegretti A, Wahl M (2014) The association between U.S. Poison Center assistance and length of stay and hospital charges. Clin Toxicol (Phila) 52(3):198–206
Harrison DL, Draugalis JR, Slack MK, Langley PC (1996) Cost-effectiveness of regional poison control centers. Arch Intern Med 156(22):2601–2608
Kearney TE, Olson KR, Bero LA, Heard SE, Blanc PD (1995) Health care cost effects of public use of a regional poison control center. West J Med 162(6):499–504
King WD, Palmisano PA (1991) Poison control centers: can their value be measured? South Med J 84(6):722–726
LoVecchio F, Curry S, Waszolek K, Klemens J, Hovseth K, Glogan D (2008) Poison control centers decrease emergency healthcare utilization costs. J Med Toxicol 4(4):221–224
Miller TR, Lestina DC (1997) Costs of poisoning in the United States and savings from poison control centers: a benefit-cost analysis. Ann Emerg Med 29(2):239–245
Spiller HA, Griffith JR (2009) The value and evolving role of the U.S. Poison Control Center System. Public Health Rep 124(3):359–363
Offerman SR (2011) The clinical management of acetaminophen poisoning in a community hospital system: factors associated with hospital length of stay. J Med Toxicol 7(1):4–11
Vassilev ZP, Marcus SM (2007) The impact of a poison control center on the length of hospital stay for patients with poisoning. J Toxicol Environ Health A 70(2):107–110
Zaloshnja E, Miller T, Jones P et al (2006) The potential impact of poison control centers on rural hospitalization rates for poisoning. Pediatrics 118(5):2094–2100
Zaloshnja E, Miller T, Jones P et al (2008) The impact of poison control centers on poisoning-related visits to EDs—United States, 2003. Am J Emerg Med 26(3):310–315
Clark RF, Williams SR, Nordt SP, Pearigen PD, Deutsch R (1998) Resource-use analysis of a medical toxicology consultation service. Ann Emerg Med 31(6):705–709
Lee V, Kerr JF, Braitberg G et al (2001) Impact of a toxicology service on a metropolitan teaching hospital. Emerg Med (Fremantle) 13(1):37–42
Premier Inc. (2014) In. https://www.premierinc.com/wps/portal/premierinc/public/aboutpremier/missionvision Accessed June 2 2014
Swanson SJ, Miller DL, McKenna RJ Jr et al (2014) Comparing robot-assisted thoracic surgical lobectomy with conventional video-assisted thoracic surgical lobectomy and wedge resection: results from a multihospital database (Premier). J Thorac Cardiovasc Surg 147(3):929–937
Kroch E, Duan M (2008) CareScience Risk Assessment Model: Hospital Performance Measurement. Agency for Healthcare Research and Quality
Boyd J 3rd, Samaddar K, Parra-Roide L, Allen EP, White B (2006) Comparison of outcome measures for a traditional pediatric faculty service and nonfaculty hospitalist services in a community teaching hospital. Pediatrics 118(4):1327–1331
Allenet B, Schmidlin S, Genty C, Bosson JL (2012) Antipsychotic drugs and risk of pulmonary embolism. Pharmacoepidemiol Drug Saf 21(1):42–48
Dulisse B, Li X, Gayle JA et al (2013) A retrospective study of the clinical and economic burden during hospitalizations among cancer patients with febrile neutropenia. J Med Econ 16(6):720–735
Main ML, Ryan AC, Davis TE, Albano MP, Kusnetzky LL, Hibberd M (2008) Acute mortality in hospitalized patients undergoing echocardiography with and without an ultrasound contrast agent (multicenter registry results in 4,300,966 consecutive patients). Am J Cardiol 102(12):1742–1746
Premier Inc. (2014) Premier Research Services: Published Research. In. https://www.premierinc.com/wps/wcm/connect/a730127b-0690-413a-9167-7e6b2ebd0134/PRS_PublishedResearch_Oct2013.pdf?MOD=AJPERES Accessed April 9, 2014
Schneeweiss S, Seeger JD, Landon J, Walker AM (2008) Aprotinin during coronary-artery bypass grafting and risk of death. N Engl J Med 358(8):771–783
Celso B, Tepas J, Langland-Orban B et al (2006) A systematic review and meta-analysis comparing outcome of severely injured patients treated in trauma centers following the establishment of trauma systems. J Trauma 60(2):371–378, discussion 378
Pollack MM, Cuerdon TT, Patel KM, Ruttimann UE, Getson PR, Levetown M (1994) Impact of quality-of-care factors on pediatric intensive care unit mortality. JAMA 272(12):941–946
Pollack MM, Patel KM, Ruttimann E (1997) Pediatric critical care training programs have a positive effect on pediatric intensive care mortality. Crit Care Med 25(10):1637–1642
Smith JS Jr, Martin LF, Young WW, Macioce DP (1990) Do trauma centers improve outcome over non-trauma centers: the evaluation of regional trauma care using discharge abstract data and patient management categories. J Trauma 30(12):1533–1538
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The authors sincerely thank and acknowledge Michael Duan and John Martin of Premier Healthcare Solutions, Inc., for their insights and assistance regarding the study design and Premier® methodologies.
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All authors are employees of Banner Health.
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Curry, S.C., Brooks, D.E., Skolnik, A.B. et al. Effect of a Medical Toxicology Admitting Service on Length of Stay, Cost, and Mortality Among Inpatients Discharged with Poisoning-Related Diagnoses. J. Med. Toxicol. 11, 65–72 (2015). https://doi.org/10.1007/s13181-014-0418-z
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DOI: https://doi.org/10.1007/s13181-014-0418-z