Abstract
Coronary computer tomographic angiography (CCTA) for screening intra-arterial vessel disease is gaining rapid clinical acceptance in recent years, but its use for such assessments in metal-stented vessel segments is very limited due to blooming artifacts introduced by the metal. However, vessel segments treated by the polymeric everolimus-eluting bioresorbable vascular scaffolds (Absorb) are readily monitored for intravascular disease over time with CCTA. The data on the accuracy of multi-detector computed tomography (MDCT) in patients treated with Absorb is still sparse. Results on 5 Japanese case studies from ABSORB EXTEND are presented here. Five patients were treated with Absorb, and follow-up angiography was conducted at 8 to 14 months as per routine site standard of practice. 320-row MDCT scan was performed within 1 month before the angiography. By MDCT, all Absorb-treated lesions were clearly evaluated and restenosis were not observed. Minimal diameter and % diameter stenosis were similar between MDCT and quantitative angiography (2.07 ± 0.13 vs. 2.03 ± 0.06 mm, P = 0.86, and 22.5 ± 5.0 vs. 21.5 ± 4.5 %, P = 0.88, respectively). MDCT appears to be feasible and useful for evaluating lumen patency and vessel disease in segments implanted with Absorb at follow-up.
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The authors thank all of the patients for their participation in this study.
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This research received no grant from any funding agency in the public, commercial, or not-for-profit sectors.
Disclosure
Patrick W. Serruys is member of Advisory Board of Abbott Vascular. Alexandre Abizaid receives research grants from Abbott Vascular. Shigeru Saito receives consultancy from Terumo Corporation and receives remuneration from Abbott Vascular Japan, Medtronic, and Boston Scientific Japan. Yoshinobu Onuma is member of Advisory Board of Abbott Vascular Japan. Takeshi Kimura receives research funding from Abbott Vascular Japan and Terumo Corporation. Charles A. Simonton is a full time employee of Abbott Vascular. Kengo Tanabe receives consultancy from Terumo Corporation, Kaneka Medix Corporation and Zeon Medical receives remuneration from Abbott Vascular Japan. None of the other authors have conflicts of interest of declare. The ABSORB EXTEND single arm study is sponsored and funded by Abbott Vascular.
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Asami, M., Aoki, J., Serruys, P.W. et al. Feasibility of 320-row multi-detector computed tomography angiography to assess bioabsorbable everolimus-eluting vascular scaffolds. Cardiovasc Interv and Ther 31, 96–100 (2016). https://doi.org/10.1007/s12928-015-0353-1
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DOI: https://doi.org/10.1007/s12928-015-0353-1