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Conversion of Aneurysmal Bone Cyst into Fibrous Dysplasia: A Rare Pediatric Case Report

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Abstract

Aneurysmal bone cyst (ABC) is an uncommon, non-neoplastic, expansive and erosive bone lesion. Considered as a pseudocyst due the lack of epithelial lining, the presence of giant cells and similarity to other lesions can make preoperative diagnosis difficult; biopsy findings must be co-related to complete clinical and radiological assessment. ABC’s controversial etiopathogenesis and variable clinicopathological presentations have been widely described, but to date, there are just a few reports in literature describing the development of fibrous dysplasia (FD) from an ABC, and even less cases occurring in the jaws. We describe the case of an ABC in an 8 year-old male patient, affecting the body of the mandible, which showed accelerated growth associated to thinning of the buccal, lingual and lower cortical plates. The treatment consisted of repetitive surgical resection, curettage of the lesion and mandibular reinforcement with osteosynthesis reconstruction plates. A 16-month follow-up showed self-limitation of the overgrowth. The final histopathological and radiological analysis confirmed the FD diagnosis.

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References

  1. Jaffe HL, Lichtenstein L (1942) Solitary unicameral bone cyst with emphasis on the roentgen picture, the pathologic appearance and the pathogenesis. Arch Surg 44:1004–1025

    Article  Google Scholar 

  2. Rai KK, Dharmendrasinh R, Shiva HR (2012) Aneurysmal bone cyst: a lesion of the mandibular condyle. J Maxillofac Oral Surg 11:238–242

    Article  PubMed  Google Scholar 

  3. Omami G, Mathew R, Gianoli D, Lurie A (2012) Enormous aneurysmal bone cyst of the mandible: and radiologic-pathologic correlation. Oral Surg Oral Med Oral Pathol Oral Radiol 114:75–79

    Article  Google Scholar 

  4. Biesecker JL, Marcove RC, Huvos AG, Mike V (1970) Aneurysmal bone cysts. A clinicopathologic study of 66 cases. Cancer 26:615–625

    Article  CAS  PubMed  Google Scholar 

  5. Sun ZJ, Zhao YF, Yang RL, Zwahlen RA (2010) Aneurysmal bone cysts of the jaws: analysis of 17 cases. J Oral Maxillofac Surg 68:2122–2128

    Article  PubMed  Google Scholar 

  6. Shear M, Speight P (2007) Cysts of the oral and maxillofacial region. Blackwell, Oxford

    Book  Google Scholar 

  7. Sakuma T, Yamamoto N, Onda T, Sugahara K, Yamamoto M et al (2013) Aneurysmal bone cyst in the mandible: report of 2 cases and review of literature. J Oral Maxillofac Surg Med Pathol 25:129–133

    Article  Google Scholar 

  8. Kiattavorncharoen S, Joos U, Brinksschmidt C, Werkmeister R (2003) Aneurysmal bone cyst of the mandible: a case report. Int J Oral Maxillofac Surg 32:419–422

    Article  CAS  PubMed  Google Scholar 

  9. Roychoudhury A, Rustagi A, Bhatt K, Bhutia O, Seith A (2009) Aneurysmal bone cyst of the mandible: report of 3 cases. J Oral Maxillofac Surg 67:1996–2004

    Article  PubMed  Google Scholar 

  10. Kalantar MH (1998) Aneurysmal bone cysts of the jaws: clinicopathological features, radiographic evaluation and treatment analysis of 17 cases. J Craniomaxillofac Surg 26:56–62

    Article  Google Scholar 

  11. Kalantar MH, Navi F, Eshkevari PS, Jafari SM, Shams MG et al (2008) Variable presentations of aneurysmal bone cysts of the jaws: 51 cases treated during a 30-year period. J Oral Maxillofac Surg 66:2098–2103

    Article  Google Scholar 

  12. Buraczewski J, Dabska M (1971) Pathogenesis of aneurysmal bone cyst. Cancer 28:597–604

    Article  CAS  PubMed  Google Scholar 

  13. Lichtenstein L, Jaffe HL (1942) Fibrous dysplasia of bone: a condition affecting one, several or many bones. Arch Pathol 33:777–816

    Google Scholar 

  14. Waldron CA (1993) Fibro-osseous lesions of the jaws. J Oral Maxillofac Surg 51:828–835

    Article  CAS  PubMed  Google Scholar 

  15. Sadeghi SM, Hosseini SN (2011) Spontaneous conversion of fibrous dysplasia into osteosarcoma. J Craniofac Surg 22:959–961

    Article  PubMed  Google Scholar 

  16. Arden RL, Bahu SJ, Lucas DR (1997) Mandibular aneurysmal bone cyst associated with fibrous dysplasia. Otolaryngol Head Neck Surg 117:153–156

    Article  Google Scholar 

  17. Diercks RL, Sauter AJ, Mallens WM (1986) Aneurysmal bone cyst in association with fibrous dysplasia: a case report. J Bone Joint Surg 68:144–146

    CAS  Google Scholar 

  18. Haddad GF, Hambali F, Mufarrij A, Nassar A, Haddad FS (1998) Concomitant fibrous dysplasia and aneurysmal bone cyst of the skull base. Pediatr Neurosurg 28:147–153

    Article  CAS  PubMed  Google Scholar 

  19. Claus-Hermberg H, Lozano MP, Pozzo MJ (2011) Aneurysmal bone cyst in cranial fibrous dysplasia. Bone 48:S286–S287

    Google Scholar 

  20. Clough JR, Price CHG (1968) Aneurysmal bone cysts: review of 12 cases. J Bone Joint Surg 50:116–127

    CAS  Google Scholar 

  21. Buraczewski J, Dabska M (1971) Pathogenesis of aneurysmal bone cyst: relationship between aneurysmal bone cyst and fibrous dysplasia of bone. Cancer 28:597–604

    Article  CAS  PubMed  Google Scholar 

  22. Jaffe HL (1962) Discussion on Donaldson’s paper. J Bone Joint Surg 44-A:25–40

  23. Dabska M, Buraczewski J (1972) On malignant transformation in fibrous dysplasia of bone. Oncology 26:369–383

    Article  CAS  PubMed  Google Scholar 

  24. Jaffe HL (1950) Aneurysmal bone cyst. Bull Hosp Joint Dis 1950(11):3–13

    Google Scholar 

  25. Lichtenstein L (1950) Aneurysmal bone cyst: a pathological entity commonly mistaken for giant-cell tumour and occasionally for hemangioma and osteogenic sarcoma. Cancer 3:279–289

    Article  Google Scholar 

  26. Lichtenstein L (1953) Aneurysmal bone cyst: further observations. Cancer 6:1228–1237

    Article  CAS  PubMed  Google Scholar 

  27. Donaldson WF (1962) Aneurysmal bone cyst. J Bone Joint Surg 44-A:25–39

Download references

Acknowledgments

The authors want to thank Jaime Perna and the personnel of the Instituto de Neurociencias Clínica del Sol, Barranquilla. We also want to thank Viviana Bertiller and the Instituto Quirúrgico del Norte for kindly processing and interpreting the histologic plates, and their generous assistance with the histopathologic analysis of this case. For the latter, we also want to thank María Rosa Buenahora, Universidad El Bosque, Bogotá, Colombia.

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Correspondence to Andrés Gómez-Delgado.

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Arango-Fernández, H., Pineda, S., Elneser, N. et al. Conversion of Aneurysmal Bone Cyst into Fibrous Dysplasia: A Rare Pediatric Case Report. J. Maxillofac. Oral Surg. 15 (Suppl 2), 355–360 (2016). https://doi.org/10.1007/s12663-016-0899-1

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  • DOI: https://doi.org/10.1007/s12663-016-0899-1

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