Skip to main content

Advertisement

SpringerLink
Log in

Pituitary Adenoma Leads to Adenoid Cystic Carcinoma in the Oral Cavity: An Intriguing Case

  • Case Report
  • Published:
Journal of Maxillofacial and Oral Surgery Aims and scope Submit manuscript

Abstract

Adenoid cystic carcinoma is a tumor of the exocrine glands originating primarily from the minor salivary glands. Though rare but there has been incidences of its spread into intracranial sites via different routes. We report of an intriguing case of remote metastasis of intracranial tumor in the pituitary diagnosed as pituitary adenoma which spread to the oral cavity as adenoid cystic carcinoma. To our knowledge, this is the first reported case of seeding of cells from intra cranial pituitary adenoma to intra-oral site manifesting as adenoid cystic carcinoma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

References

  1. Fortuna A, Gambacorta D (1971) Cylindroma in the region of the gasserian ganglion: case report. J Neurosurg 34:427–431

    Article  CAS  PubMed  Google Scholar 

  2. Koka VN, Tiwari RM, van der Waal I, Snow GB, Nauta J, Karim AB, Tierie AH (1989) Adenoid cystic carcinoma of the salivary glands: clinicopathological survey of 51 patients. J Laryngol Otol 103:675–679

    Article  CAS  PubMed  Google Scholar 

  3. Alleyne CH, Bakay RA, Costigan D, Thomas B, Joseph GJ (1996) Intracranial adenoid cystic carcinoma: case report and review of the literature. Surg Neurol 45:265–271

    Article  CAS  PubMed  Google Scholar 

  4. Gormley WB, Sekhar LN, Wright DC, Olding M, Janecka IP, Snyderman CH (1996) Richardson management and long-term outcome of adenoid cystic carcinoma with intracranial extension: a neurosurgical perspective. Neurosurgery 38:1105–1113

    CAS  PubMed  Google Scholar 

  5. Kawamata T, Harashima S, Kubo O, Hori T (2006) Intrasellar remote metastasis from adenoid cystic carcinoma of parotid gland: case report. Endocr J 53(5):659–663

    Article  PubMed  Google Scholar 

  6. Bradley PJ (2004) Adenoid cystic carcinoma of the head and neck: a review. Curr Opin Otolaryngol Head Neck Surg 12(2):127–132

    Article  PubMed  Google Scholar 

  7. Tincani AJ, Del Negro A, Araújo PP, Akashi HK, Martins AS, Altemani AM, Barreto G (2006) Management of salivary gland adenoid cystic carcinoma: institutional experience of a case series. Sao Paulo Med J 124(1):26–30

    Article  PubMed  Google Scholar 

  8. Chundru NSV, Amudala R (2013) Adenoid cystic carcinoma of palate: A case report and review of literature. Dent Res J (Isfahan) 10(2):274–278

    Article  Google Scholar 

  9. Kim HK, Sung MW, Chung PS, Rhee CS, Park CI, Kim WH (1994) Adenoid cystic carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 120:721–726

    Article  CAS  PubMed  Google Scholar 

  10. Szanto PA, Luna MA, Tortoledo ME, White RA (1984) Histologic grading of adenoid cystic carcinoma of the salivary glands. Cancer 54:1062–1065

    Article  CAS  PubMed  Google Scholar 

  11. Gnepp DR, Henley JD, Roderick HW, Simpson Eveson J (2009) Salivary and lacrimal glands. In: Gnepp Douglas R (ed) Diagnostic surgical pathology of the Head and Neck, 2nd edn. Saunders, Philadelphia, pp 482–486

    Google Scholar 

  12. Xhang X (2013) Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas. J Clin Endocrinol Metab 82(2):654–658

    Google Scholar 

  13. Qi ZZ, Liu J, Liu FY, Sun CF (2013) Effect of pituitary tumour transforming gene on invasion and metastasis of salivary adenoid cystic carcinoma. Shanghai Kou Qiang Yi Xue 22(6):667–670

    CAS  PubMed  Google Scholar 

  14. Famini P, Maya MM, Melmed S (2011) Pituitary magnetic resonance imaging for sellar and parasellar masses: ten-year experience in 2598 patients. J Clin Endocrinol Metab 96(6):1633–1641

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Ezzat S, Asa SL, Couldwell WT et al (2004) The prevalence of pituitary adenomas: a systematic review. Cancer 101(3):613–619

    Article  PubMed  Google Scholar 

  16. Wang J, Ma E-m, Peng-fei W, Qiu B, Wang Y-j (2014) Multiple intracranial and spinal metastases from a nonfunctioning pituitary adenoma following multiple surgeries: an illustrative case with16 years of follow-up. World J Surg Oncol 12:380–387

    Article  PubMed  PubMed Central  Google Scholar 

  17. Daly AF, Rixhon M, Adam C, Dempegioti A, Tichomirowa MA, Beckers A (2006) High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium. J Clin Endocrinol Metab 91(12):4769–4775

    Article  CAS  PubMed  Google Scholar 

  18. Kaltsas GA, Nomikos P, Kontogeorgos G, Buchfelder M, Grossman AB (2005) Clinical review: diagnosis and management of pituitary carcinomas. J Clin Endocrinol Metab 90(5):3089–3099

    Article  CAS  PubMed  Google Scholar 

  19. Matsuki M, Kaji Y, Matsuo M, Kobashi Y (2000) MR findings of subarachnoid dissemination of a pituitary adenoma. Br J Radiol 73:783–785

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery, V.S Dental College, Bangalore, India

    R. Keerthi & Abhishek Dutta

Authors
  1. R. Keerthi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Abhishek Dutta
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Abhishek Dutta.

Ethics declarations

Conflict of interest

Authors declare that we do not have any conflict of interest with any funding body or organization.

Ethical Approval

No human or animal subjects were involved in the study so no need was felt for ethical clearance.

Informed Consent

No human subjects involved so no informed consent has been taken.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Keerthi, R., Dutta, A. Pituitary Adenoma Leads to Adenoid Cystic Carcinoma in the Oral Cavity: An Intriguing Case. J. Maxillofac. Oral Surg. 15 (Suppl 2), 343–345 (2016). https://doi.org/10.1007/s12663-015-0876-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12663-015-0876-0

Keywords

Search

Navigation