Abstract
In recent years, nanodiamonds have emerged from primarily an industrial and mechanical applications base, to potentially underpinning sophisticated new technologies in biomedical and quantum science. Nanodiamonds are relatively inexpensive, biocompatible, easy to surface functionalise and optically stable. This combination of physical properties are ideally suited to biological applications, including intracellular labelling and tracking, extracellular drug delivery and adsorptive detection of bioactive molecules. Here we describe some of the methods and challenges for processing nanodiamond materials, detection schemes and some of the leading applications currently under investigation.
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References
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Acknowledgements
We acknowledge Carlo Bradac for his artistic rendering of an NV centre. We would also like to acknowledge the support from the Australian Research Council Future Fellowship scheme (FT0991243), Discovery Projects scheme (DP1094439) and Centres of Excellence (CE110001013). JMS is also supported by an International Macquarie Research Excellence Scholarship and NJCK acknowledges support from the National Health and Medical Research Council Project Grant 512413.
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The authors would like to acknowledge that since this is a review and as such does not present any unpublished experimental work by our group that the ethical standards of Australia were upheld.
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The authors declare that they have no conflict of interest.
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Say, J.M., van Vreden, C., Reilly, D.J. et al. Luminescent nanodiamonds for biomedical applications. Biophys Rev 3, 171–184 (2011). https://doi.org/10.1007/s12551-011-0056-5
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DOI: https://doi.org/10.1007/s12551-011-0056-5