Abstract
Climacteric women are able to become pregnant using oocytes donated earlier in life. However, adverse effects on such donated oocytes have been identified. We report a case of a successful dichorionic diamniotic twin pregnancy achieved using autologous fertilized cryopreserved oocytes in a climacteric woman. A 51-year-old woman became pregnant using autologous fertilized oocytes that had been frozen for 15 years. On her first visit, multiple leiomyoma of the uterus and gestational diabetes mellitus were diagnosed, and proteinuria began to appear at 30 weeks. In spite of our concerns these complications did not exacerbate and the clinical course for both mother and neonates was favorable. This is the first report of a live twin birth achieved using autologous cryopreserved oocytes in a climacteric woman. This case report may be of value to women who desire postponement of their infertility treatment and the professional assisted reproduction community.
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The authors wish to thank Dr. Fumikazu Kotsuji for his critical review of this manuscript.
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This case report was not supported by any grant or funding.
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Tomoki Kotera, Takashi Shibata, Hiroki Kato, Hirohiko Watanabe, Satoshi Nakago declare that there are no conflicts of interest.
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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and its later amendments. Informed consent was obtained from all patients for being included in the study.
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This article does not contain any studies with animal subjects performed by the any of authors.
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Kotera, T., Shibata, T., Kato, H. et al. Twin pregnancy in a 51-year-old woman who underwent autologous cryopreservation at the age of 36 years: case report. Reprod Med Biol 15, 187–189 (2016). https://doi.org/10.1007/s12522-015-0230-8
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DOI: https://doi.org/10.1007/s12522-015-0230-8