Abstract
Mesenteric neuroendocrine tumors are usually metastases originating from the small intestine; however, primary mesenteric cases are rare. We present an interesting case of a mesenteric neuroendocrine tumor that changed its internal composition from cystic to solid. A 72-year-old male visited our hospital because of epigastralgia 4 years earlier. A 25-mm tumor was recognized around the terminal duodenum on computed tomography and magnetic resonance imaging, and was diagnosed as a cystic lesion. Over the following 2 years, the tumor grew to 40 mm and its internal composition changed from cystic to solid. The lesion showed positive findings on fluorodeoxyglucose positron emission tomography. Upon laparotomy, a solid tumor was detected in the mesentery of the jejunum near the ligament of Treitz. The tumor was extracted without intestinal resection and was diagnosed as a low-grade neuroendocrine tumor after histopathological and immunohistochemical examination. One year has passed since the operation, and there has been no recurrence.
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References
Pelage JP, Soyer P, Boudiaf M, et al. Carcinoid tumors of the abdomen: CT features. Abdom Imaging. 1999;24:240–5.
Sheth S, Horton KM, Garland MR, et al. Mesenteric neoplasms: CT appearances of primary and secondary tumors and differential diagnosis. Radiographics. 2003;23:457–73.
Ligneau B, Lombard-Bohas C, Partensky C, et al. Cystic endocrine tumors of the pancreas: clinical, radiologic, and histopathologic features in 13 cases. Am J Surg Pathol. 2001;25:752–60.
Barnardo DE, Stavrou M, Bourne R, et al. Primary carcinoid tumor of the mesentery. Hum Pathol. 1984;15:796–8.
Modlin IM, Kidd M, Latich I, et al. Current status of gastrointestinal carcinoids. Gastroenterology. 2005;128:1717–51.
Masui T, Doi R, Ito T, et al. Diagnostic value of (18)F-fluorodeoxyglucose positron emission tomography for pancreatic neuroendocrine tumors with reference to the World Health Organization classification. Oncol Lett. 2010;1:155–9.
Kubota K, Okasaki M, Minamimoto R, et al. Lesion-based analysis of (18)F-FDG uptake and (111)In-Pentetreotide uptake by neuroendocrine tumors. Ann Nucl Med. 2014;28:1004–10.
Garin E, Le Jeune F, Devillers A, et al. Predictive value of 18F-FDG PET and somatostatin receptor scintigraphy in patients with metastatic endocrine tumors. J Nucl Med. 2009;50:858–64.
Yang M, Ke NW, Zeng L, et al. Survival analyses for patients with surgically resected pancreatic neuroendocrine tumors by world health organization 2010 grading classifications and american joint committee on cancer 2010 staging systems. Medicine. 2015;94:e2156.
Yamaguchi T, Fujimori T, Tomita S, et al. Clinical validation of the gastrointestinal NET grading system: Ki67 index criteria of the WHO 2010 classification is appropriate to predict metastasis or recurrence. Diagn Pathol. 2013;8:65.
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Akira Yasuda, Hidehiko Kitagami, Yasuhiro Kondo, Keisuke Nonoyama, Kaori Watanabe, Shiro Fujihata, Hirotaka Miyai, Minoru Yamamoto, Yasunobu Shimizu and Moritsugu Tanaka declare that they have no conflict of interest.
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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.
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Yasuda, A., Kitagami, H., Kondo, Y. et al. Primary mesenteric neuroendocrine tumor that changed its internal composition from cystic to solid: a case report. Clin J Gastroenterol 10, 18–22 (2017). https://doi.org/10.1007/s12328-016-0695-y
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DOI: https://doi.org/10.1007/s12328-016-0695-y