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Idiopathic hypereosinophilic syndrome presenting with hepatitis and achalasia

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Abstract

Idiopathic hypereosinophilic syndrome (HES) is a rare diagnosis defined by the World Health Organization as a persistent eosinophilia for 6 months and resulting in end-organ dysfunction. While many patients present with nonspecific symptoms, others will present with symptoms of the affected organs, most commonly those involving the heart, skin, or nervous system. Gastrointestinal or liver involvement is estimated to affect up to one-third of patients with HES, although patients with clinically significant disease are limited to case reports. This is the first report of a patient presenting with hepatitis and achalasia related to idiopathic HES.

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Acknowledgments

Financial disclosure: none to report. No individuals participated in the writing of this case report other than those listed as authors above.

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Authors and Affiliations

  1. Division of Gastroenterology and Hepatology, Department of Internal Medicine, SSM Health Saint Louis University Hospital, 3635 Vista Avenue, Saint Louis, MO, 63110, USA

    Amanda C. Cheung & Christine Y. Hachem

  2. Division of Anatomic Pathology, Department of Pathology, SSM Health Saint Louis University Hospital, Saint Louis, MO, USA

    Jinping Lai

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  1. Amanda C. Cheung
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  2. Christine Y. Hachem
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Correspondence to Amanda C. Cheung.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Cheung, A.C., Hachem, C.Y. & Lai, J. Idiopathic hypereosinophilic syndrome presenting with hepatitis and achalasia. Clin J Gastroenterol 9, 238–242 (2016). https://doi.org/10.1007/s12328-016-0661-8

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  • DOI: https://doi.org/10.1007/s12328-016-0661-8

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